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TNFAIP1 Knockout Cell Lines

Gene: TNFAIP1

Official Full Name: TNF alpha induced protein 1provided by HGNC

Gene Summary: This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34975 TNFAIP1 Knockout cell line (HeLa) Human TNFAIP1 1:3~1:6 Negative Online Inquiry
KO34976 TNFAIP1 Knockout cell line (HCT 116) Human TNFAIP1 1:2~1:4 Negative Online Inquiry
KO34977 TNFAIP1 Knockout cell line (HEK293) Human TNFAIP1 1:3~1:6 Negative Online Inquiry
KO34978 TNFAIP1 Knockout cell line (A549) Human TNFAIP1 1:3~1:4 Negative Online Inquiry

Background

TNFAIP1 Gene Knockout Cell Lines are genetically engineered cellular systems designed to enable the study of TNFAIP1 (tumor necrosis factor alpha-induced protein 1), a protein implicated in various cellular processes, including inflammation, apoptosis, and immune response modulation. These knockout cell lines are specifically modified to lack the TNFAIP1 gene, providing researchers with valuable tools for analyzing the gene's role in disease mechanisms and therapeutic responses.

The primary function of the TNFAIP1 Gene Knockout Cell Lines lies in their ability to facilitate elucidation of TNFAIP1's biological pathways. By observing how cellular behavior changes in the absence of TNFAIP1, researchers can identify associated signaling cascades, impact on cell survival, and alterations in immune interactions. This insight is critical for understanding the pathological roles of TNFAIP1 in conditions such as autoimmune diseases and cancer, thus informing both research and therapeutic strategies.

In clinical and research settings, the application of these knockout cell lines is significant. They serve as invaluable models for screening potential drugs, understanding disease mechanisms, and developing interventions targeting TNFAIP1. Moreover, they can be used in combinatorial studies with other genetic models to explore complex signaling networks and therapeutic approaches.

A key advantage of our TNFAIP1 Gene Knockout Cell Lines is their enhanced specificity and reliability compared to other gene-editing strategies, such as CRISPR/Cas9. These cell lines offer a well-characterized and reproducible system, ensuring that research outcomes are consistent and applicable across various experimental conditions. Additionally, our product is validated for use in multiple cell types, broadening its applicability for diverse research inquiries.

For researchers and clinicians aiming to advance their understanding of TNFAIP1-related pathways or to explore novel therapeutic avenues, these knockout cell lines represent an essential resource. Our company prides itself on delivering high-quality biological products, backed by extensive expertise in genetic engineering and cellular biology, ensuring that our offerings meet the rigorous demands of modern scientific investigation.

Please note that all services are for research use only. Not intended for any clinical use.

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