Gene: TMEM30A
Official Full Name: transmembrane protein 30Aprovided by HGNC
Gene Summary: Enables aminophospholipid flippase activity and structural molecule activity. Involved in several processes, including phospholipid transport; positive regulation of transport; and xenobiotic transmembrane transport. Located in endoplasmic reticulum and plasma membrane. Part of early endosome membrane; late endosome membrane; and phospholipid-translocating ATPase complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05170 | TMEM30A Knockout cell line (HeLa) | Human | TMEM30A | 1:3~1:6 | Negative | Online Inquiry |
KO05171 | TMEM30A Knockout cell line (HCT 116) | Human | TMEM30A | 1:2~1:4 | Negative | Online Inquiry |
KO05172 | TMEM30A Knockout cell line (HEK293) | Human | TMEM30A | 1:3~1:6 | Negative | Online Inquiry |
KO05173 | TMEM30A Knockout cell line (A549) | Human | TMEM30A | 1:3~1:4 | Negative | Online Inquiry |
TMEM30A Gene Knockout Cell Lines are genetically engineered systems that lack the expression of the TMEM30A gene, a critical component involved in various cellular processes, including membrane dynamics and lipid metabolism. By utilizing CRISPR/Cas9 genome editing techniques, these cell lines facilitate comprehensive studies into the functional roles of TMEM30A in both physiological and pathological contexts.
The primary function of TMEM30A is to contribute to the assembly and stability of the P4-ATPase flippase complex, which is essential for the translocation of phospholipids across cellular membranes. By studying these knockout cell lines, researchers can gain insights into the implications of TMEM30A deficiency on cellular homeostasis, signaling pathways, and lipid distribution. The mechanistic understanding attained through these models enables the exploration of potential therapeutic targets for a range of diseases, including cancer and metabolic disorders.
In the research and clinical realm, the availability of TMEM30A Gene Knockout Cell Lines holds significant scientific importance. They serve as valuable tools for drug discovery, toxicity assessments, and in-depth functional genomics studies. This capability to rapidly assess the implications of gene loss, coupled with their robust and reproducible nature, makes these cell lines superior to standard models, which may not fully elucidate gene function.
What sets our TMEM30A Gene Knockout Cell Lines apart from alternatives on the market is their high efficiency of edits and the confirmed knockout at both RNA and protein levels, ensuring that researchers can trust the validity of their experimental outcomes. This exceptional specificity and reliability enable target users—ranging from academic researchers to biopharmaceutical companies—to make informed decisions driven by accurate data.
In summary, TMEM30A Gene Knockout Cell Lines are an indispensable asset for researchers looking to deepen their understanding of cellular mechanisms and discover novel therapeutic options. Backed by a company with extensive expertise in gene editing technologies and cellular biology, we are proud to offer products that empower scientific advancement and enhance research productivity.
Please note that all services are for research use only. Not intended for any clinical use.
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