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TMEM229B Knockout Cell Lines

Gene: TMEM229B

Official Full Name: transmembrane protein 229Bprovided by HGNC

Gene Summary: Predicted to act upstream of or within macrophage activation and response to bacterium. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13201 TMEM229B Knockout cell line (HEK293) Human TMEM229B 1:3~1:6 Negative Online Inquiry

Background

TMEM229B Gene Knockout Cell Lines are meticulously engineered cellular models designed to specifically eliminate the expression of the TMEM229B gene, a critical player in cellular signaling and membrane dynamics. These knockout cell lines provide researchers with a unique opportunity to study the role of TMEM229B in various biological processes such as cell proliferation, differentiation, and response to environmental stimuli.

The primary mechanism behind the functionality of these knockout cell lines lies in the precise application of CRISPR-Cas9 technology, which induces targeted double-strand breaks at the TMEM229B gene locus, leading to the introduction of insertions or deletions that effectively silence the gene. By disrupting this gene's expression, researchers can observe the resultant phenotypic changes, enabling them to elucidate its involvement in various pathophysiological conditions, including cancer, neurodegenerative diseases, and immune responses.

The scientific importance of TMEM229B Gene Knockout Cell Lines cannot be overstated, as they fill a critical gap in understanding gene function in a controlled environment. These cell lines are valuable for basic research, drug discovery, and developing novel therapeutic strategies in clinical settings. They facilitate the exploration of gene interactions and the mechanisms underlying disease progression, making them essential tools in molecular biology and translational research.

Distinct from traditional knockout models, TMEM229B Gene Knockout Cell Lines offer higher specificity, reduced off-target effects, and easy scalability, thereby streamlining experimental workflows. Their reliable performance in various assays, from gene expression to cellular behavior analysis, enhances their appeal and usability across multiple research disciplines.

The value of these knockout cell lines to researchers and clinicians is profound, as they not only accelerate scientific discovery but also provide insights that could lead to innovative treatments. This aligns with our commitment to offering cutting-edge bioresearch tools backed by scientific excellence. Our company stands at the forefront of genetic engineering technology, providing products that empower the research community to unlock new biological insights, bridging the gap between fundamental research and clinical application.

Please note that all services are for research use only. Not intended for any clinical use.

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