Gene: TMEM186
Official Full Name: transmembrane protein 186provided by HGNC
Gene Summary: This gene encodes a potential transmembrane protein. [provided by RefSeq, Dec 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO28687 | TMEM186 Knockout cell line (HeLa) | Human | TMEM186 | 1:3~1:6 | Negative | Online Inquiry |
KO28688 | TMEM186 Knockout cell line (HCT 116) | Human | TMEM186 | 1:2~1:4 | Negative | Online Inquiry |
KO28689 | TMEM186 Knockout cell line (HEK293) | Human | TMEM186 | 1:3~1:6 | Negative | Online Inquiry |
KO28690 | TMEM186 Knockout cell line (A549) | Human | TMEM186 | 1:3~1:4 | Negative | Online Inquiry |
TMEM186 Gene Knockout Cell Lines are specially designed mammalian cell lines that have undergone targeted gene editing to disrupt the expression of the TMEM186 gene. This innovation serves as a vital tool in cellular and molecular biology, enabling researchers to investigate the functions of the TMEM186 protein and its implications in various biological processes. By employing techniques such as CRISPR/Cas9, these knockout cell lines provide a precise means of elucidating gene function, pinpointing pathways connected to diseases, and facilitating drug discovery efforts.
The primary function of the TMEM186 Gene Knockout Cell Lines is to permit the analysis of cellular phenotypes resulting from the absence of the TMEM186 gene. This product allows researchers to study alterations in cellular behavior, signaling pathways, and genetic interactions in a controlled environment. The unique mechanisms behind these alterations offer insights into the gene's role in physiological processes and pathologies, such as cancer or neurodegenerative diseases.
This product holds significant scientific importance in both research and clinical arenas, as it presents opportunities for biomarker discovery and therapeutic target validation. In research settings, the availability of knockout models enables high-throughput screening and comparative analyses with wild-type cells, enhancing the understanding of gene function and its relevance in disease mechanisms. Clinically, elucidating the role of TMEM186 paves the way for potential therapeutic interventions.
A key advantage of using TMEM186 Gene Knockout Cell Lines lies in their specificity and reliability compared to traditional knockdown approaches. Unlike RNA interference that may cause partial reduction of gene expression, gene knockout provides complete loss-of-function, offering clearer experimental outcomes. Furthermore, these cell lines serve as an invaluable complement to existing resources, broadening the scope of experimental design.
For researchers and clinicians seeking to deepen their understanding of gene functionality or develop novel therapeutics, the TMEM186 Gene Knockout Cell Lines represent an indispensable resource that accelerates progress in their studies. Our company specializes in providing high-quality biological products tailored for cutting-edge research applications, equipped with a commitment to supporting your scientific endeavors with precision and reliability.
Please note that all services are for research use only. Not intended for any clinical use.
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