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TMEM121B Knockout Cell Lines

Gene: TMEM121B

Official Full Name: transmembrane protein 121Bprovided by HGNC

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27594 TMEM121B Knockout cell line (HCT 116) Human TMEM121B 1:2~1:4 Negative Online Inquiry
KO27595 TMEM121B Knockout cell line (HEK293) Human TMEM121B 1:3~1:6 Negative Online Inquiry

Background

TMEM121B Gene Knockout Cell Lines are a specialized set of genetically engineered cell lines that facilitate the study of the TMEM121B gene's function in cellular mechanisms and disease. Utilizing CRISPR/Cas9 technology, these cell lines have been developed to achieve a precise disruption of the TMEM121B gene, allowing researchers to investigate the resultant phenotypic changes in cellular behavior, interaction, and signaling pathways. By eliminating the expression of TMEM121B, scientists can elucidate its role in physiological processes, such as cell proliferation, differentiation, and response to various stimuli.

The key function of these knockout cell lines lies in their ability to serve as a model for dissecting the biological significance of TMEM121B in both normal and pathological states. Research applications span a wide range of disciplines, including cancer biology, neurobiology, and regenerative medicine, making the insights derived from these cell lines crucial for understanding how alterations in TMEM121B expression may contribute to disease mechanisms and potential therapeutic strategies.

Compared to traditional gene manipulation methods, the CRISPR/Cas9 technique offers a higher specificity and efficiency in generating knockout lines, thereby providing a more reliable tool for researchers. This specificity minimizes off-target effects that can compromise experimental results and increases confidence in the data obtained.

The value of TMEM121B Gene Knockout Cell Lines is particularly pronounced for researchers and clinicians aiming to uncover novel targets for therapeutic intervention or biomarkers for disease prognosis. By utilizing these cell lines, users can streamline their research processes and advance their understanding of complex biological systems involving TMEM121B.

As a leader in the development of genetically modified models, our company is committed to providing high-quality biological products that empower scientists to drive groundbreaking research. Our expertise in gene editing technology ensures that each cell line is rigorously validated and ready to enhance the pursuit of scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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