Gene: TMCO3
Official Full Name: transmembrane and coiled-coil domains 3provided by HGNC
Gene Summary: This gene encodes a member of the monovalent cation:proton antiporter 2 (CPA2) family of transporter proteins. Members of this family typically couple the export of monovalent cations, such as potassium or sodium, to the import of protons across cellular membranes. Mutations in this gene have been identified in patients with a rare inherited vision defect, cornea guttata with anterior polar cataract. [provided by RefSeq, Mar 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20896 | TMCO3 Knockout cell line (HeLa) | Human | TMCO3 | 1:3~1:6 | Negative | Online Inquiry |
KO20897 | TMCO3 Knockout cell line (HCT 116) | Human | TMCO3 | 1:2~1:4 | Negative | Online Inquiry |
KO20898 | TMCO3 Knockout cell line (HEK293) | Human | TMCO3 | 1:3~1:6 | Negative | Online Inquiry |
KO20899 | TMCO3 Knockout cell line (A549) | Human | TMCO3 | 1:3~1:4 | Negative | Online Inquiry |
TMCO3 Gene Knockout Cell Lines are specifically engineered cellular models designed to study the biological functions and pathways associated with the TMCO3 gene. This innovative tool allows researchers to investigate the role of TMCO3 in various cellular processes and diseases, particularly in the area of metabolic regulation and cellular stress responses. By utilizing CRISPR-Cas9 technology, these knockout cell lines offer precise and efficient disruption of the TMCO3 gene, leading to a thorough understanding of its contributions to physiological and pathological conditions.
The key function of TMCO3 Gene Knockout Cell Lines centers on their ability to elucidate the mechanisms by which the TMCO3 protein influences cellular homeostasis, calcium signaling, and endoplasmic reticulum stress. Researchers can observe the resulting phenotypic changes, which may provide insights into diseases such as obesity, diabetes, and neurodegenerative disorders. The ability to manipulate the expression of the TMCO3 gene allows for a comprehensive analysis of transduction pathways, promoting advancements in targeted therapies and precision medicine.
The scientific importance of these knockout cell lines extends into both research and clinical applications. In research settings, they provide a vital platform for drug screening, genetic studies, and the exploration of gene-environment interactions. Clinically, understanding the role of TMCO3 may lead to novel biomarkers and therapeutic targets for metabolic diseases, making these cell lines invaluable to both academia and the biotech industry.
What sets TMCO3 Gene Knockout Cell Lines apart from alternatives is their high specificity and robust phenotype characterization, ensuring reliable results in experiments. Additionally, their compatibility with various assays, including cell viability, apoptosis, and metabolic profiling, enhances their applicability across different research fields.
With a commitment to advancing scientific discovery, our company is dedicated to providing high-quality biological products and tools, including the TMCO3 Gene Knockout Cell Lines. Our expertise in genetic engineering and cell line development enables researchers and clinicians to achieve groundbreaking insights into complex biological systems, ultimately accelerating the pace of innovation in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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