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TIMM23 Knockout Cell Lines

Gene: TIMM23

Official Full Name: translocase of inner mitochondrial membrane 23provided by HGNC

Gene Summary: The protein encoded by this gene is part of a complex located in the inner mitochondrial membrane that mediates the transport of transit peptide-containing proteins across the membrane. Multiple transcript variants, one protein-coding and others not protein-coding, have been found for this gene. [provided by RefSeq, Jul 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13399 TIMM23 Knockout cell line (HeLa) Human TIMM23 1:3~1:6 Negative Online Inquiry
KO13400 TIMM23 Knockout cell line (HCT 116) Human TIMM23 1:2~1:4 Negative Online Inquiry
KO13401 TIMM23 Knockout cell line (HEK293) Human TIMM23 1:3~1:6 Negative Online Inquiry
KO13402 TIMM23 Knockout cell line (A549) Human TIMM23 1:3~1:4 Negative Online Inquiry

Background

TIMM23 Gene Knockout Cell Lines represent a pivotal resource in the field of molecular biology and genetic research, specifically focused on elucidating the functions of the TIMM23 gene, which encodes a crucial component of the mitochondrial import machinery. These genetically engineered cell lines exhibit a complete knockout of the TIMM23 gene, allowing researchers to investigate the gene's role in mitochondrial biogenesis, protein import, and overall cellular metabolism.

The primary function of TIMM23 within cellular mechanisms is to facilitate the translocation of proteins across the mitochondrial inner membrane. This process is vital for maintaining mitochondrial function and influencing a variety of cellular processes such as apoptosis and energy metabolism. By utilizing TIMM23 Knockout Cell Lines, researchers can explore the downstream effects of disrupted mitochondrial protein import, leading to a better understanding of mitochondrial diseases and potential therapeutic targets.

The scientific significance of these knockout cell lines extends from basic research to clinical applications. They serve as valuable tools for studying diseases linked to mitochondrial dysfunction, including neurodegenerative disorders, metabolic syndromes, and aging. Additionally, they can be employed in drug discovery initiatives aimed at identifying compounds that may restore normal mitochondrial function.

Unlike other gene knockout models, TIMM23 Gene Knockout Cell Lines offer high specificity and reproducibility, essential for generating reliable data. Their unique genetic modifications ensure minimal off-target effects, a common issue in broader gene editing approaches. Furthermore, these cell lines are supported by a suite of characterization data, facilitating experimental design and enhancing confidence in results.

In summary, TIMM23 Gene Knockout Cell Lines are an indispensable asset for researchers and clinicians seeking to unravel the complexities of mitochondrial biology. Their application potential, coupled with our company’s expertise in developing high-quality biological products, positions us as a leader in providing advanced tools for the scientific community. By choosing our TIMM23 Knockout Cell Lines, users benefit from cutting-edge technology combined with a commitment to excellence in support of their critical research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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