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TIAM2 Knockout Cell Lines

Gene: TIAM2

Official Full Name: TIAM Rac1 associated GEF 2provided by HGNC

Gene Summary: This gene encodes a guanine nucleotide exchange factor. A highly similar mouse protein specifically activates ras-related C3 botulinum substrate 1, converting this Rho-like guanosine triphosphatase (GTPase) from a guanosine diphosphate-bound inactive state to a guanosine triphosphate-bound active state. The encoded protein may play a role in neural cell development. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28200 TIAM2 Knockout cell line (HeLa) Human TIAM2 1:3~1:6 Negative Online Inquiry
KO28201 TIAM2 Knockout cell line (HCT 116) Human TIAM2 1:2~1:4 Negative Online Inquiry
KO28202 TIAM2 Knockout cell line (HEK293) Human TIAM2 1:3~1:6 Negative Online Inquiry
KO28203 TIAM2 Knockout cell line (A549) Human TIAM2 1:3~1:4 Negative Online Inquiry

Background

TIAM2 Gene Knockout Cell Lines are specially engineered cellular models designed to silence the expression of the TIAM2 gene, a critical regulator involved in various cellular signaling pathways such as cell adhesion, migration, and proliferation. By utilizing advanced CRISPR/Cas9 gene-editing technology, these cell lines provide researchers with a powerful tool to study the impact of TIAM2 on cellular behavior and its role in various biological processes.

The primary mechanism by which these knockout cell lines function is through the targeted disruption of the TIAM2 gene sequence. This results in a loss of TIAM2 protein expression, allowing for the observation of downstream effects on key cellular pathways. This makes TIAM2 knockout cell lines invaluable for dissecting mechanisms of diseases, particularly those linked to aberrant cell migration and cancer metastasis, as well as for identifying potential therapeutic targets.

In the realm of scientific research, TIAM2 Gene Knockout Cell Lines are crucial for elucidating the function of TIAM2 in processes such as neuronal development and immune response modulation. They serve as a foundation for studies in cancer biology, neurobiology, and developmental biology, offering insights into pathophysiological mechanisms that can drive innovation in therapeutic strategies.

What sets our TIAM2 Gene Knockout Cell Lines apart from alternatives is their high efficiency and specificity. Each line is rigorously validated to ensure that the knockout is complete and stable, reducing the risks of off-target effects frequently associated with other gene editing methods. Additionally, they are available in multiple cell types, increasing their applicability across various research disciplines.

For researchers and clinicians, the availability of TIAM2 Gene Knockout Cell Lines significantly enhances experimental design and translational research, particularly in drug discovery and disease modeling. Our commitment to quality and innovation is reflected in our extensive portfolio of biological research products. With years of expertise in cellular models, we ensure that our offerings empower the scientific community to unlock new discoveries and foster advancements in human health.

Please note that all services are for research use only. Not intended for any clinical use.

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