Gene: THUMPD3
Official Full Name: THUMP domain 3 tRNA guanosine methyltransferaseprovided by HGNC
Gene Summary: Enables tRNA (guanine(6)-N2)-methyltransferase activity and tRNA (guanine(7)-N2)-methyltransferase activity. Involved in tRNA methylation. Located in cytosol and nucleolus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04300 | THUMPD3 Knockout cell line (HeLa) | Human | THUMPD3 | 1:3~1:6 | Negative | Online Inquiry |
KO04301 | THUMPD3 Knockout cell line (HCT 116) | Human | THUMPD3 | 1:2~1:4 | Negative | Online Inquiry |
KO04302 | THUMPD3 Knockout cell line (HEK293) | Human | THUMPD3 | 1:3~1:6 | Negative | Online Inquiry |
KO04303 | THUMPD3 Knockout cell line (A549) | Human | THUMPD3 | 1:3~1:4 | Negative | Online Inquiry |
THUMPD3 Gene Knockout Cell Lines are a powerful research tool designed to facilitate the functional analysis of the THUMPD3 gene, a critical player in various cellular processes, including RNA metabolism and gene regulation. These engineered cell lines have been developed using CRISPR-Cas9 technology to create specific null mutations, allowing researchers to examine the phenotypic consequences of THUMPD3 loss. By providing a controlled system where the impact of gene deletion can be precisely studied, these cell lines enable scientists to explore the role of THUMPD3 in disease mechanisms, cellular stress responses, and other biological functions.
The THUMPD3 gene has garnered attention in both basic and clinical research settings due to its implications in various disorders, including cancer and neurodegenerative diseases. The knockout cell lines serve as a robust platform for examining gene function, unraveling gene regulatory networks, and screening for potential drug targets. By eradicating the THUMPD3 expression in these well-characterized background cell lines, researchers can isolate gene-specific pathways and contribute to the broader understanding of gene interactions and cellular behavior.
One of the distinct advantages of THUMPD3 Gene Knockout Cell Lines is their versatility compared to other gene interrogation methods, such as RNA interference or traditional knockout approaches. CRISPR-generated knockouts offer greater specificity and efficiency, minimizing off-target effects and providing a more reliable model for researchers. Additionally, these cell lines come with extensive documentation and validated protocols, ensuring ease of use and reproducibility in experimental setups.
For researchers and clinicians alike, leveraging the THUMPD3 knockouts can lead to novel discoveries and insights that could pave the way for innovative therapeutic strategies. The ability to manipulate this gene directly aligns with the growing demand for precise molecular research tools in an age of personalized medicine.
At [Company Name], we specialize in producing high-quality, genetically engineered cell lines tailored for cutting-edge research. Our commitment to scientific excellence ensures that our customers receive trustworthy products that enhance their research capabilities and propel scientific discoveries forward.
Please note that all services are for research use only. Not intended for any clinical use.
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