Gene: THAP7
Official Full Name: THAP domain containing 7provided by HGNC
Gene Summary: Enables several functions, including C2H2 zinc finger domain binding activity; histone binding activity; and histone deacetylase binding activity. Involved in chromatin organization and negative regulation of transcription by RNA polymerase II. Located in chromatin; nuclear membrane; and nuclear speck. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO04659 | THAP7 Knockout cell line (HeLa) | Human | THAP7 | 1:3~1:6 | Negative | Online Inquiry |
KO04660 | THAP7 Knockout cell line (HCT 116) | Human | THAP7 | 1:2~1:4 | Negative | Online Inquiry |
KO04661 | THAP7 Knockout cell line (HEK293) | Human | THAP7 | 1:3~1:6 | Negative | Online Inquiry |
KO04662 | THAP7 Knockout cell line (A549) | Human | THAP7 | 1:3~1:4 | Negative | Online Inquiry |
THAP7 Gene Knockout Cell Lines are meticulously developed cellular models designed to study the role of the THAP7 gene, which is implicated in various biological processes, including gene regulation and cellular response to stress. These cell lines have undergone precise genetic modification techniques, such as CRISPR-Cas9, to effectively disrupt the THAP7 gene's expression, allowing researchers to investigate the downstream effects of its knockout in both physiological and pathological contexts.
The primary function of these knockout cell lines is to enable the elucidation of gene function by assessing phenotypic changes resulting from the absence of THAP7. Researchers can utilize these models to explore pathways related to cell proliferation, differentiation, or apoptosis, thereby gaining insight into diseases where THAP7 is a potential contributor. The mechanisms by which these cellular alterations manifest can be analyzed through various assays, including qPCR, Western blotting, or high-content imaging, making them an essential tool in functional genomics.
Scientifically, THAP7 Gene Knockout Cell Lines serve as a critical asset in research settings focused on cancer biology, neurobiology, and genetic disorders, where understanding the role of genes is paramount. Their application can facilitate the identification of genetic interactions and potentially uncover novel therapeutic targets.
Compared to traditional cell lines, these knockout models offer significant advantages, including higher specificity of gene disruption and the ability to validate potential drug targets in real-time. Additionally, they provide a consistent and reproducible experimental platform, reducing variability in experimental outcomes.
For researchers and clinicians, the value of THAP7 Gene Knockout Cell Lines lies not only in their technical superiority but also in their capacity to advance precision medicine initiatives. By integrating these models into their studies, users can enhance their understanding of disease mechanisms and potentially expedite the development of targeted therapies.
At [Your Company], we leverage cutting-edge genetic engineering techniques and extensive expertise in cellular biology to produce high-quality biological products. Our commitment to supporting scientific advancement ensures that researchers have access to innovative tools like THAP7 Gene Knockout Cell Lines, fostering breakthroughs in understanding genetic contributions to disease.
Please note that all services are for research use only. Not intended for any clinical use.
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