Gene: TFDP1
Official Full Name: transcription factor Dp-1provided by HGNC
Gene Summary: This gene encodes a member of a family of transcription factors that heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. The encoded protein functions as part of this complex to control the transcriptional activity of numerous genes involved in cell cycle progression from G1 to S phase. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1, 15, and X.[provided by RefSeq, Jan 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO11455 | TFDP1 Knockout cell line (HeLa) | Human | TFDP1 | 1:3~1:6 | Negative | Online Inquiry |
KO11456 | TFDP1 Knockout cell line (HCT 116) | Human | TFDP1 | 1:2~1:4 | Negative | Online Inquiry |
KO11457 | TFDP1 Knockout cell line (HEK293) | Human | TFDP1 | 1:3~1:6 | Negative | Online Inquiry |
TFDP1 Gene Knockout Cell Lines are specialized cellular models that have been genetically engineered to disrupt the expression of the TFDP1 gene, a critical component in the regulation of cell cycle and transcriptional control. This knockout technology utilizes precise gene editing techniques to create a loss-of-function mutation in the TFDP1 gene, allowing researchers to investigate the role of this gene in various biological processes, including cellular proliferation, apoptosis, and DNA repair mechanisms.
The primary function of TFDP1 in cellular systems is to form heterodimers with transcription factors and regulate gene expression by modulating the activity of E2F transcription factors. By employing TFDP1 Gene Knockout Cell Lines, scientists are able to dissect the complex signaling pathways associated with cell cycle progression and understand the impact of TFDP1 loss on tumorigenesis. This makes these cell lines invaluable for cancer research and therapeutic development, particularly regarding the efficacy of novel anti-cancer drugs or targeted therapies.
Scientific research has increasingly highlighted the involvement of TFDP1 in various malignancies, making these knockout cell lines an important tool for elucidating the molecular underpinnings of cancer. Moreover, they hold substantial applications in drug screening, where researchers can assess the effects of compounds in the absence of TFDP1 function.
Compared to alternative models, such as wild-type or transient knockdown systems, TFDP1 Gene Knockout Cell Lines offer a stable and long-term solution for studying TFDP1-related pathways. This stability significantly reduces variability and enhances reproducibility in experimental results.
For researchers and clinicians seeking to advance their understanding of cellular mechanisms or develop targeted therapies, our TFDP1 Gene Knockout Cell Lines provide a robust platform for innovative discoveries in molecular biology. With a commitment to excellence in biological product development, our company is at the forefront of providing high-quality research tools that empower scientific advancement and therapeutic innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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