Gene: TFCP2L1
Official Full Name: transcription factor CP2 like 1provided by HGNC
Gene Summary: Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27018 | TFCP2L1 Knockout cell line (HCT 116) | Human | TFCP2L1 | 1:2~1:4 | Negative | Online Inquiry |
KO27019 | TFCP2L1 Knockout cell line (HEK293) | Human | TFCP2L1 | 1:3~1:6 | Negative | Online Inquiry |
KO27020 | TFCP2L1 Knockout cell line (A549) | Human | TFCP2L1 | 1:3~1:4 | Negative | Online Inquiry |
TFCP2L1 Gene Knockout Cell Lines are specifically engineered cellular models characterized by the targeted disruption of the TFCP2L1 gene, which encodes a transcription factor integral to cellular differentiation and pluripotency. By employing state-of-the-art CRISPR/Cas9 genome-editing technology, these cell lines provide researchers with a robust tool to investigate the intricate roles of TFCP2L1 in developmental biology, cancer research, and stem cell biology.
The primary mechanism by which these cell lines function involves the elimination of TFCP2L1 expression, allowing for the analysis of downstream genetic pathways and phenotypic alterations that arise from its loss. This knockout model enables researchers to dissect the molecular regulations governing cellular processes such as proliferation, apoptosis, and differentiation, thereby illuminating the fundamental biological functions attributed to this transcription factor.
In terms of scientific significance, TFCP2L1 Gene Knockout Cell Lines serve pivotal roles in both basic and translational research. They have applications in enhancing our understanding of pluripotent stem cell maintenance and in elucidating mechanisms of tumorigenesis, especially in identifying novel therapeutic targets in cancers reliant on TFCP2L1.
What sets these knockout cell lines apart from traditional models is their precision and reproducibility. Unlike non-specific knockdown approaches, CRISPR-mediated knockout provides a more complete and permanent disruption of gene function, making results more reliable. Furthermore, these cell lines are standardly validated for consistent performance, ensuring researchers can rely on experimental outcomes.
For researchers and clinicians, the value of TFCP2L1 Gene Knockout Cell Lines lies in their potential to accelerate discoveries that can lead to innovative therapies and treatments. The ability to manipulate key genes with precision in a controlled environment represents an invaluable resource in the quest for understanding complex biological systems.
Our company has a rich expertise in providing high-quality biological products tailored for research and clinical applications, ensuring that our customers have access to cutting-edge tools that facilitate groundbreaking discoveries in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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