Gene: TEX14
Official Full Name: testis expressed 14, intercellular bridge forming factorprovided by HGNC
Gene Summary: The protein encoded by this gene is necessary for intercellular bridges in germ cells, which are required for spermatogenesis. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13455 | TEX14 Knockout cell line (HCT 116) | Human | TEX14 | 1:2~1:4 | Negative | Online Inquiry |
KO13456 | TEX14 Knockout cell line (HEK293) | Human | TEX14 | 1:3~1:6 | Negative | Online Inquiry |
TEX14 Gene Knockout Cell Lines are genetically modified cell lines designed to study the function of the TEX14 gene, which plays a crucial role in cell division and the formation of specialized cellular structures called intercellular bridges. By employing CRISPR-Cas9 technology, these cell lines have been meticulously engineered to disrupt the TEX14 gene, providing researchers with a powerful tool to investigate its biological processes and implications in disease.
The primary mechanism underlying the functionality of TEX14 Gene Knockout Cell Lines involves the elimination of TEX14 protein expression, which is essential for maintaining the integrity of cytokinesis during cell division. When TEX14 is knocked out, researchers can observe changes in cell morphology, division rates, and intercellular communication, thereby gaining insights into the gene's role in various cellular and developmental pathways. This is particularly relevant in the context of studying diseases such as cancer, where dysregulation of cell division is often a contributing factor.
In research and clinical applications, these cell lines are invaluable for investigating cellular behavior in response to treatment and understanding the molecular basis of diseases linked to aberrant cell division. Moreover, TEX14 Gene Knockout Cell Lines can serve as a platform for drug discovery, allowing scientists to screen for compounds that may rescue or exacerbate the phenotypes associated with TEX14 loss.
Compared to other gene knockout models, TEX14 Gene Knockout Cell Lines provide specificity and reliability due to the targeted nature of CRISPR-Cas9 modifications, which minimizes off-target effects commonly associated with earlier methods. Additionally, these cell lines are ready-to-use, enabling researchers to expedite their studies without the added time and resource investments typically required for generating and validating new knockout models.
The value of TEX14 Gene Knockout Cell Lines lies in their ability to unlock new avenues of research and therapeutic exploration, making them essential tools for researchers and clinicians alike in the fields of cell biology and oncology. Our company specializes in producing high-quality genetically modified cell lines, ensuring that our products not only meet the rigorous demands of scientific research but also contribute meaningfully to advancing healthcare solutions.
Please note that all services are for research use only. Not intended for any clinical use.
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