Gene: TCHP
Official Full Name: trichoplein keratin filament bindingprovided by HGNC
Gene Summary: Involved in apoptotic process; negative regulation of cell growth; and negative regulation of cilium assembly. Located in several cellular components, including apical cortex; cytoskeleton; and mitochondrion. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25036 | TCHP Knockout cell line (HeLa) | Human | TCHP | 1:3~1:6 | Negative | Online Inquiry |
KO25037 | TCHP Knockout cell line (HCT 116) | Human | TCHP | 1:2~1:4 | Negative | Online Inquiry |
KO25038 | TCHP Knockout cell line (HEK293) | Human | TCHP | 1:3~1:6 | Negative | Online Inquiry |
KO25039 | TCHP Knockout cell line (A549) | Human | TCHP | 1:3~1:4 | Negative | Online Inquiry |
TCHP Gene Knockout Cell Lines are genetically modified cell lines that have undergone targeted gene disruption to facilitate in-depth functional studies of the TCHP (thyroid cancer-associated protein) gene. This product serves as a vital tool in understanding the physiological roles of TCHP and its implications in various cellular processes, particularly in cancer biology. By employing techniques such as CRISPR-Cas9 or homologous recombination, these cell lines exhibit a complete knockout of the TCHP gene, enabling researchers to investigate the downstream effects of its loss on cellular functions, signaling pathways, and overall cellular behavior.
The utility of TCHP Gene Knockout Cell Lines is particularly significant in both research and clinical settings. Scientists exploring the mechanisms of thyroid cancer progression, cellular differentiation, and tumor microenvironment can utilize these cell lines to gain insights into how the absence of TCHP alters genetic expression patterns and phenotypic outcomes. Moreover, their application extends into drug discovery and development, where understanding gene function through knockout models can inform therapeutic strategies targeting TCHP-related pathways.
These cell lines stand out due to their validated genetic modification, ensuring precise and reproducible results. Unlike traditional methods that may not precisely eliminate gene function, our knockout cell lines provide a robust platform for high-throughput screening and functional genomics studies. Additionally, they come with detailed characterization to support effective experimental design, offering a superior alternative to lesser-validated models.
For researchers and clinicians, the TCHP Gene Knockout Cell Lines not only serve as a reliable experimental resource but also enable breakthroughs in understanding complex biological mechanisms linked to cancer. By selecting our product, users align themselves with a dedicated company whose expertise encompasses cutting-edge genetic engineering and cell line development, ensuring consistent quality and scientific rigor to foster innovation in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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