Gene: TCEAL9
Official Full Name: transcription elongation factor A like 9provided by HGNC
Gene Summary: The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein. This gene also encodes a domain with similarity to the transcription elongation factor A, SII-related family. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO02863 | TCEAL9 Knockout cell line (HeLa) | Human | TCEAL9 | 1:3~1:6 | Negative | Online Inquiry |
KO02864 | TCEAL9 Knockout cell line (HCT 116) | Human | TCEAL9 | 1:2~1:4 | Negative | Online Inquiry |
KO02865 | TCEAL9 Knockout cell line (HEK293) | Human | TCEAL9 | 1:3~1:6 | Negative | Online Inquiry |
KO02866 | TCEAL9 Knockout cell line (A549) | Human | TCEAL9 | 1:3~1:4 | Negative | Online Inquiry |
TCEAL9 Gene Knockout Cell Lines represent a sophisticated tool for researchers investigating gene function, cellular mechanisms, and disease pathways. These cell lines are engineered through the CRISPR-Cas9 gene editing technology to disrupt the TCEAL9 gene, a member of the TEA domain family implicated in various biological processes such as transcriptional regulation and cancer progression. By knocking out this specific gene, researchers can elucidate TCEAL9's role in cellular proliferation, differentiation, and apoptosis, providing critical insights into its function in normal physiology and pathological conditions.
The mechanism behind TCEAL9 gene knockout involves precise genomic edits that result in a loss-of-function phenotype, allowing for comprehensive studies on the resultant phenotypic alterations. This process enables researchers to explore the gene’s contributions to signaling pathways, its interactions with other cellular components, and its overall impact on cellular behavior. Such investigations are invaluable in cellular biology, cancer research, and the development of therapeutic strategies.
The scientific importance of TCEAL9 Knockout Cell Lines extends beyond basic research; they are pivotal in translational studies aimed at developing targeted therapies for diseases where TCEAL9 is involved. Additionally, the knockout model serves as a benchmark for validating findings from other experimental systems, thereby enhancing the reproducibility and reliability of research outcomes.
Compared to alternative models, such as transient knockdown techniques or conventional knockout mice, TCEAL9 Gene Knockout Cell Lines offer superior stability and scalability for long-term studies, as well as a more controlled environment for experimental reproducibility. This makes them particularly advantageous in high-throughput screening settings or when investigating specific pharmacological interventions.
For researchers and clinicians alike, the value of TCEAL9 Gene Knockout Cell Lines lies in their ability to drive meaningful discoveries with significant implications for understanding complex biological systems and disease mechanisms. Our commitment to providing high-quality products is backed by extensive expertise in gene editing technologies, ensuring that your research is supported with innovative and validated tools that propel scientific advancement.
Please note that all services are for research use only. Not intended for any clinical use.
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