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TBRG1 Knockout Cell Lines

Gene: TBRG1

Official Full Name: transforming growth factor beta regulator 1provided by HGNC

Gene Summary: Involved in several processes, including DNA replication; protein localization to nucleoplasm; and protein stabilization. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO24526 TBRG1 Knockout cell line (HeLa) Human TBRG1 1:3~1:6 Negative Online Inquiry
KO24527 TBRG1 Knockout cell line (HCT 116) Human TBRG1 1:2~1:4 Negative Online Inquiry
KO24528 TBRG1 Knockout cell line (HEK293) Human TBRG1 1:3~1:6 Negative Online Inquiry
KO24529 TBRG1 Knockout cell line (A549) Human TBRG1 1:3~1:4 Negative Online Inquiry

Background

TBRG1 Gene Knockout Cell Lines are specialized in vitro models that have been genetically modified to disrupt the function of the TBRG1 gene, a critical regulator of various cellular processes, including cell proliferation and differentiation. These knockout cell lines serve as invaluable tools for researchers studying the role of TBRG1 in cellular signaling pathways and its implications in diseases such as cancer and developmental disorders.

The primary mechanism by which these cell lines operate involves the targeted disruption of the TBRG1 gene, achieved through advanced genome editing techniques such as CRISPR/Cas9. This precise alteration allows scientists to observe the phenotypic consequences of TBRG1 deficiency, shedding light on its putative biological functions and interactions within different cellular contexts. By examining the effects of TBRG1 knockout, researchers can elucidate the gene's potential roles in tumorigenesis or its involvement in specific signaling cascades.

The scientific importance of TBRG1 Gene Knockout Cell Lines lies in their applicability across various research domains. They provide a stable platform for drug discovery, mechanism-of-action studies, and the development of targeted therapies. These cell lines facilitate high-throughput screening, enabling rapid identification of compounds that can modulate TBRG1-related pathways, thus accelerating translational research and clinical applications.

In comparison to other genetic models, such as TBRG1 overexpression systems or wild-type counterparts, these knockout cell lines offer a more distinct and relevant representation of TBRG1’s functional roles under loss-of-function conditions. Researchers benefit from the specificity of these models, which can lead to more robust and reproducible results in both basic and applied research settings.

Investing in TBRG1 Gene Knockout Cell Lines is essential for researchers and clinicians who are focused on understanding the complexities of genetic regulation in disease and therapeutic intervention. Our company is committed to providing high-quality, validated biological products that empower research initiatives and drive innovation in genomics and molecular biology. With our expertise in genetic engineering and cellular models, we ensure that our offerings meet the highest standards of scientific rigor, promoting reliability and efficiency in your research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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