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TBC1D23 Knockout Cell Lines

Gene: TBC1D23

Official Full Name: TBC1 domain family member 23provided by HGNC

Gene Summary: Involved in brain development; retrograde transport, endosome to Golgi; and vesicle tethering to Golgi. Located in WASH complex; cytoplasmic vesicle; and trans-Golgi network. Implicated in pontocerebellar hypoplasia type 11. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13531 TBC1D23 Knockout cell line (HeLa) Human TBC1D23 1:3~1:6 Negative Online Inquiry
KO13532 TBC1D23 Knockout cell line (HCT 116) Human TBC1D23 1:2~1:4 Negative Online Inquiry
KO13533 TBC1D23 Knockout cell line (HEK293) Human TBC1D23 1:3~1:6 Negative Online Inquiry
KO13534 TBC1D23 Knockout cell line (A549) Human TBC1D23 1:3~1:4 Negative Online Inquiry

Background

TBC1D23 Gene Knockout Cell Lines are specifically engineered cellular systems that have undergone targeted gene editing to disrupt the expression of the TBC1D23 gene. This gene is known to play a pivotal role in cellular processes such as autophagy, endosomal trafficking, and cellular signaling pathways. Utilizing advanced CRISPR-Cas9 technology, these knockout cell lines provide researchers with a powerful tool to study the functional consequences of TBC1D23 loss in a controlled environment, allowing for in-depth analysis of its involvement in diseases like cancer, neurodegeneration, and metabolic disorders.

The primary mechanism of TBC1D23 function revolves around its role as a Rab GTPase-activating protein, influencing vesicular transport within the cell. By inhibiting the GTPase activity of Rab proteins, TBC1D23 regulates endosomal trafficking and autophagic processes, which are essential for maintaining cellular homeostasis. Researchers utilizing these knockout cell lines can investigate the downstream effects of TBC1D23 depletion, unveiling new insights into various pathological states and potential therapeutic targets.

The scientific importance of TBC1D23 Gene Knockout Cell Lines is underscored by their applications in both basic research and clinical settings. Their ability to model specific gene knockouts makes them invaluable for drug discovery, gene function studies, and understanding complex biological signaling networks. Unlike conventional cell lines, these knockout variants allow for precise dissection of TBC1D23-related pathways, ensuring reproducibility and relevance to human disease mechanisms.

One of the key advantages of our TBC1D23 Gene Knockout Cell Lines is their readiness for immediate use, coupled with consistent performance across a range of experimental conditions. This contrasts with traditional methods that may require extensive validation and optimization. In addition, the knockout efficiency and specificity have been rigorously assessed to enhance experimental reliability and precision.

For researchers and clinicians alike, the utility of TBC1D23 Gene Knockout Cell Lines translates into clearer insights and faster progress towards discovery and innovation within the biomedical field. The ability to study gene function in a knockout model accelerates research timelines, enabling more robust and credible results, which can influence new clinical applications.

As a leader in providing advanced biological products, our company excels in developing high-quality, customizable genetic tools that meet the rigorous demands of modern research. With a commitment to innovation and scientific integrity, we offer products that empower researchers in the pursuit of knowledge and therapeutic advancements.

Please note that all services are for research use only. Not intended for any clinical use.

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