Gene: TAS2R33
Official Full Name: taste 2 receptor member 33provided by HGNC
Gene Summary: Predicted to enable G protein-coupled receptor activity and bitter taste receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and detection of chemical stimulus involved in sensory perception of bitter taste. Predicted to be located in plasma membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13579 | TAS2R33 Knockout cell line (HeLa) | Human | TAS2R33 | 1:3~1:6 | Negative | Online Inquiry |
KO13580 | TAS2R33 Knockout cell line (HCT 116) | Human | TAS2R33 | 1:2~1:4 | Negative | Online Inquiry |
KO13581 | TAS2R33 Knockout cell line (HEK293) | Human | TAS2R33 | 1:3~1:6 | Negative | Online Inquiry |
KO13582 | TAS2R33 Knockout cell line (A549) | Human | TAS2R33 | 1:3~1:4 | Negative | Online Inquiry |
TAS2R33 Gene Knockout Cell Lines are specialized cellular models generated through advanced CRISPR/Cas9 gene editing technology, designed to study the function and pharmacology of the TAS2R33 gene, which encodes for a bitter taste receptor. This product allows researchers to explore the receptor’s role in various physiological processes, including its involvement in food preference, metabolic regulation, and innate immune responses. By creating a knockout model, where the TAS2R33 gene is inactivated, researchers can isolate and elucidate the effects of this receptor in both normal and pathological conditions.
The key function of these cell lines lies in their ability to facilitate extensive investigations into the signaling pathways activated by the TAS2R33 receptor. Researchers can utilize these cell lines to assess how TAS2R33 influences cellular responses to bitter compounds and its potential implications in taste sensation and aversion behavior. Furthermore, these models can be pivotal in exploring the associations between bitter taste perception and various health conditions, including obesity and metabolic disorders.
The scientific importance of TAS2R33 Gene Knockout Cell Lines is underscored by their versatility in both research and clinical settings. These models offer significant advantages for drug discovery and development, particularly in identifying novel pharmacological agents targeting taste receptors. Additionally, their use extends to personalized medicine, where understanding receptor functionality can lead to tailored therapeutic approaches based on individual taste profiles.
Unlike conventional cell lines that express the TAS2R33 gene, these knockout models ensure a clear interpretation of data by eliminating confounding variables that may arise from receptor activation. This precision makes them particularly appealing to researchers looking for reliable insights into the complex interplay of taste receptors and metabolic processes.
By choosing TAS2R33 Gene Knockout Cell Lines, researchers and clinicians gain access to a powerful tool that enhances the understanding of taste perception and its broader implications in health and disease. Our company prides itself on its commitment to offering high-quality, scientifically validated biological products, backed by a team of experts in molecular biology and genetics, ensuring that users receive the best resources for their research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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