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SZT2 Knockout Cell Lines

Gene: SZT2

Official Full Name: SZT2 subunit of KICSTOR complexprovided by HGNC

Gene Summary: The protein encoded by this gene is expressed in the brain, predominantly in the parietal and frontal cortex as well as in dorsal root ganglia. It is localized to the peroxisome, and is implicated in resistance to oxidative stress. It likely functions by increasing superoxide dismutase (SOD) activity, but itself has no direct SOD activity. Studies in mice show that this gene confers low seizure threshold, and may also enhance epileptogenesis. [provided by RefSeq, Jun 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO29435 SZT2 Knockout cell line (HeLa) Human SZT2 1:3~1:6 Negative Online Inquiry
KO29436 SZT2 Knockout cell line (HCT 116) Human SZT2 1:2~1:4 Negative Online Inquiry
KO29437 SZT2 Knockout cell line (HEK293) Human SZT2 1:3~1:6 Negative Online Inquiry
KO29438 SZT2 Knockout cell line (A549) Human SZT2 1:3~1:4 Negative Online Inquiry

Background

SZT2 Gene Knockout Cell Lines are carefully engineered cellular models that serve as powerful tools for studying the functional implications of the SZT2 gene in diverse biological processes and disease states. These cell lines are generated using sophisticated CRISPR/Cas9 gene-editing technology, which allows for precise disruption of the SZT2 gene, enabling researchers to investigate the phenotypic consequences of its loss. The knockout of this gene is particularly relevant in contexts such as neurodevelopmental disorders and other metabolic diseases, where SZT2 has been implicated in crucial cellular pathways.

The primary function of SZT2 knockout cell lines is to facilitate in-depth functional studies by allowing researchers to observe the alterations in cellular behavior and biochemistry that occur in the absence of SZT2 activity. This includes evaluating changes in cellular signaling, metabolic pathways, and overall cell morphology. By utilizing these knockout lines, scientists can uncover the role of SZT2 in cellular processes, helping to elucidate mechanisms underlying various pathologies.

In research and clinical settings, SZT2 Gene Knockout Cell Lines hold significant scientific importance. They provide a platform for drug discovery and development, where researchers can screen for compounds that may correct the abnormal phenotypes observed in SZT2-deficient cells. Furthermore, these cell lines can assist in the validation of SZT2 as a therapeutic target, thus accelerating the movement towards potential clinical applications.

Compared to alternative models, such as wild-type cell lines or animal models, SZT2 knockout cell lines offer several advantages. They enable a faster and more efficient investigation into gene function, minimize the variability often seen in whole organisms, and allow for high-throughput screenings, making them a cost-effective resource for laboratories.

For researchers and clinicians alike, the value of SZT2 Gene Knockout Cell Lines lies in their ability to provide clear insights into gene function and disease mechanisms, ultimately aiding in the identification of novel therapeutic strategies. Our company specializes in creating high-quality, reliable cellular models that support the advancement of biomedical research. We are committed to providing tools that enhance scientific discovery and improve patient outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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