Gene: Syvn1
Official Full Name: synoviolin 1provided by RGD
Gene Summary: Predicted to enable several functions, including enzyme binding activity; protein-folding chaperone binding activity; and unfolded protein binding activity. Predicted to be involved in several processes, including proteasomal protein catabolic process; protein K48-linked ubiquitination; and protein stabilization. Predicted to act upstream of or within in utero embryonic development and negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. Predicted to be located in nucleoplasm and smooth endoplasmic reticulum. Predicted to be part of Derlin-1 retrotranslocation complex and Hrd1p ubiquitin ligase ERAD-L complex. Predicted to be active in endoplasmic reticulum quality control compartment. Orthologous to human SYVN1 (synoviolin 1). [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00182 | SYVN1 Knockout cell line (A549) | Human | SYVN1 | 1:3~1:4 | Negative | Online Inquiry |
KO09435 | SYVN1 Knockout cell line (HeLa) | Human | SYVN1 | 1:3~1:6 | Negative | Online Inquiry |
KO09436 | SYVN1 Knockout cell line (HCT 116) | Human | SYVN1 | 1:2~1:4 | Negative | Online Inquiry |
KO09437 | SYVN1 Knockout cell line (HEK293) | Human | SYVN1 | 1:3~1:6 | Negative | Online Inquiry |
Syvn1 Gene Knockout Cell Lines are advanced cellular models engineered to specifically disable the Syvn1 gene, offering valuable tools for studying the gene's role in cellular processes and disease mechanisms. These knockout cell lines are produced through precise CRISPR-Cas9 gene-editing technology, which allows for the targeted disruption of the Syvn1 gene, leading to a functional loss that enables researchers to investigate the biological implications of Syvn1 deficiency.
The key function of these cell lines is to facilitate in-depth analysis of protein interactions, signaling pathways, and the overall impact of Syvn1 on cellular homeostasis. By comparing Syvn1 knockout cells with wild-type counterparts, researchers can elucidate the gene's involvement in critical biological processes, such as protein degradation, stress response, and cellular aging. This information is vital for understanding the molecular underpinnings of various diseases, including neurodegenerative disorders and cancer, where Syvn1 has been implicated.
In clinical and research settings, Syvn1 Gene Knockout Cell Lines serve as essential resources for drug discovery, pathway elucidation, and biomarker identification. Their robust nature and reproducibility enhance the reliability of experimental results, making them superior to traditional model systems that may not accurately reflect gene function. Compared to alternatives, such as transient knockdown methods or whole-organism models, these cell lines provide a straightforward and efficient means to study gene function at a cellular level, offering high-throughput potential for screening and mechanistic studies.
For researchers and clinicians, the value of Syvn1 Gene Knockout Cell Lines lies in their ability to streamline investigations, reduce experimental variability, and accelerate discoveries in gene function and therapeutic development. These cell lines are an essential advancement for anyone looking to deepen their understanding of gene-related diseases and contribute to groundbreaking research.
Our company specializes in providing high-quality cellular models tailored for advanced research applications, ensuring that scientists have access to precise, reliable tools to drive their studies forward. With our extensive expertise in gene editing technologies and cell culture systems, we are dedicated to supporting innovative research and contributing to significant scientific advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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