Gene: SYT9
Official Full Name: synaptotagmin 9provided by HGNC
Gene Summary: Predicted to enable SNARE binding activity; calcium ion sensor activity; and calcium-dependent phospholipid binding activity. Predicted to be involved in positive regulation of vesicle fusion; regulation of calcium ion-dependent exocytosis; and vesicle-mediated transport. Predicted to be located in clathrin-coated endocytic vesicle membrane. Predicted to be active in hippocampal mossy fiber to CA3 synapse; plasma membrane; and secretory vesicle. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24177 | SYT9 Knockout cell line (HEK293) | Human | SYT9 | 1:3~1:6 | Negative | Online Inquiry |
SYT9 Gene Knockout Cell Lines are sophisticated cellular models specifically engineered to disable the SYT9 gene, which encodes the synaptotagmin-9 protein implicated in neuropeptide secretion and neurotransmitter release. These cell lines utilize CRISPR-Cas9 technology, a revolutionary gene-editing technique, to precisely create targeted deletions within the SYT9 locus. As a result, these cell lines provide invaluable tools for researchers investigating the biological roles of SYT9 in synaptic transmission, cellular signaling, and various neurobiological processes.
The primary function of SYT9 gene knockout cell lines is to serve as a platform for elucidating the molecular mechanisms underlying synaptic function. By studying the effects of SYT9 loss-of-function, researchers can identify pathways influenced by this protein and correlate deficits with behavioral or physiological changes. This insight is crucial for understanding neurological disorders linked to synaptic dysregulation, such as autism spectrum disorders and neurodegenerative diseases.
Scientifically, the importance of SYT9 gene knockout cell lines lies in their applications across both basic research and translational medicine. In academic labs, they provide meaningful insights into synaptic physiology, while in pharmaceutical settings, they can be used for drug screening and target validation in the development of new neurological therapies. Compared to traditional methods of gene silencing, such as RNA interference, the CRISPR-mediated knockout introduces stable, heritable genetic modifications that provide clearer and more reproducible experimental results.
The unique selling points of SYT9 gene knockout cell lines include their high specificity, efficiency in gene modification, and the relevance of the SYT9 gene in various neurological contexts. These characteristics make them indispensable for researchers demanding reliable models that can contribute to the understanding of complex neurobiological processes.
In conclusion, SYT9 Gene Knockout Cell Lines represent a cutting-edge resource for researchers and clinicians aiming to deepen their understanding of synaptic biology and develop innovative treatments for related disorders. Our company is dedicated to providing high-quality biological products, backed by extensive expertise in gene-editing technologies and cellular model development, positioning us as a trusted partner in advancing scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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