Gene: SYPL1
Official Full Name: synaptophysin like 1provided by HGNC
Gene Summary: Predicted to be involved in chemical synaptic transmission. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO03802 | SYPL1 Knockout cell line (HeLa) | Human | SYPL1 | 1:3~1:6 | Negative | Online Inquiry |
KO03803 | SYPL1 Knockout cell line (HCT 116) | Human | SYPL1 | 1:2~1:4 | Negative | Online Inquiry |
KO03804 | SYPL1 Knockout cell line (HEK293) | Human | SYPL1 | 1:3~1:6 | Negative | Online Inquiry |
KO03805 | SYPL1 Knockout cell line (A549) | Human | SYPL1 | 1:3~1:4 | Negative | Online Inquiry |
SYPL1 Gene Knockout Cell Lines are genetically engineered cellular models in which the SYPL1 gene has been completely inactivated, allowing researchers to study the biological implications of its absence. The SYPL1 gene encodes a protein that plays a significant role in synaptic transmission and vesicular trafficking, crucial processes in neuronal signaling. By utilizing CRISPR-Cas9 technology or similar gene-editing methods, these cell lines provide an efficient means to elucidate the functional pathways influenced by SYPL1, offering insights into neurological disorders and synaptic dysfunction.
The primary function of SYPL1 Gene Knockout Cell Lines lies in their ability to serve as a tool for dissecting molecular mechanisms in various biological contexts, particularly those related to neurobiology. These cell lines allow researchers to investigate signaling pathways, protein interactions, and cellular responses to environmental stimuli in a controlled setting. The unique knockout feature enables the observation of phenotypic changes compared to wild-type counterparts, facilitating hypothesis testing and experimental validation.
Scientifically, these cell lines are invaluable for advancing research into diseases that involve synaptic impairment, such as autism spectrum disorder or schizophrenia. They can be employed in drug discovery, target validation, and the exploration of gene therapy strategies, thereby bridging the gap between basic research and clinical applications.
In comparison to alternative models like transient transfection or overexpression systems, SYPL1 Gene Knockout Cell Lines offer the distinct advantage of mimicking physiological conditions more closely. Researchers can achieve long-term observations with stable genetic alterations, reducing variability and providing a more robust framework for experimental design.
Investing in SYPL1 Gene Knockout Cell Lines represents a strategic advantage for researchers and clinicians focused on understanding the complexities of neurobiology. These models not only streamline the research process but also enhance the validity of experimental outcomes. Our company is dedicated to providing high-quality biological products, underpinned by robust scientific expertise and a commitment to supporting innovative research in the biosciences.
Please note that all services are for research use only. Not intended for any clinical use.
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