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SYNGR2 Knockout Cell Lines

Gene: SYNGR2

Official Full Name: synaptogyrin 2provided by HGNC

Gene Summary: This gene encodes an integral membrane protein containing four transmembrane regions and a C-terminal cytoplasmic tail that is tyrosine phosphorylated. The exact function of this protein is unclear, but studies of a similar rat protein suggest that it may play a role in regulating membrane traffic in non-neuronal cells. The gene belongs to the synaptogyrin gene family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33541 SYNGR2 Knockout cell line (HeLa) Human SYNGR2 1:3~1:6 Negative Online Inquiry
KO33542 SYNGR2 Knockout cell line (HCT 116) Human SYNGR2 1:2~1:4 Negative Online Inquiry
KO33543 SYNGR2 Knockout cell line (HEK293) Human SYNGR2 1:3~1:6 Negative Online Inquiry
KO33544 SYNGR2 Knockout cell line (A549) Human SYNGR2 1:3~1:4 Negative Online Inquiry

Background

SYNGR2 Gene Knockout Cell Lines are meticulously engineered cell lines that have undergone targeted gene disruption of the SYNGR2 gene, a member of the synaptogyrin family involved in synaptic function and neurotransmitter release. This innovative product provides researchers with a powerful tool to investigate the biological roles of SYNGR2 in cellular processes such as synaptic transmission, plasticity, and neurological disorders.

The primary function of these knockout cell lines lies in their ability to facilitate the study of gene function through the observation of phenotypic changes resulting from the loss of SYNGR2 expression. By employing CRISPR-Cas9 technology, researchers can achieve precise modifications at the genetic level, enabling them to delineate the pathways affected by SYNGR2 knockouts and assess the subsequent impacts on neuronal health and function. This specificity enhances the reliability of experiments, allowing for clearer conclusions about the gene’s involvement in various biological processes.

Scientifically, SYNGR2 Gene Knockout Cell Lines hold immense value in both basic and applied research. They serve as critical models for exploring the molecular mechanisms underlying synaptic disorders, providing insights that are crucial for developing therapeutic interventions in neurological diseases like Alzheimer’s and schizophrenia. Furthermore, these cell lines can be employed in drug discovery, aiding in identifying potential pharmacological targets that modulate synaptic function.

What sets SYNGR2 Gene Knockout Cell Lines apart from alternative products is their validation and reproducibility. Each batch of cell lines is stringently characterized for gene disruption efficiency and functional outcomes, which is key in ensuring that researchers obtain consistent results in their studies. Additionally, their easy integration into existing research workflows enhances usability and efficiency.

In summary, SYNGR2 Gene Knockout Cell Lines represent a valuable asset for researchers and clinicians committed to unraveling the complexities of synaptic biology and related disorders. Our company, with its extensive experience in genetic engineering and a commitment to quality, offers these cell lines as part of a larger suite of biological products aimed at advancing scientific discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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