Gene: SUV39H2
Official Full Name: SUV39H2 histone lysine methyltransferaseprovided by HGNC
Gene Summary: Enables cation binding activity; histone H3K9 methyltransferase activity; and ubiquitin-like ligase-substrate adaptor activity. Involved in epigenetic programming in the zygotic pronuclei. Acts upstream of or within cellular response to hypoxia and negative regulation of transcription by RNA polymerase II. Located in chromatin. Is active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20740 | SUV39H2 Knockout cell line (HeLa) | Human | SUV39H2 | 1:3~1:6 | Negative | Online Inquiry |
KO20741 | SUV39H2 Knockout cell line (HCT 116) | Human | SUV39H2 | 1:2~1:4 | Negative | Online Inquiry |
KO20742 | SUV39H2 Knockout cell line (HEK293) | Human | SUV39H2 | 1:3~1:6 | Negative | Online Inquiry |
KO20743 | SUV39H2 Knockout cell line (A549) | Human | SUV39H2 | 1:3~1:4 | Negative | Online Inquiry |
SUV39H2 Gene Knockout Cell Lines are innovative biological tools designed to study the function of the SUV39H2 gene, a crucial component involved in the regulation of chromatin modification and gene expression. These cell lines have been engineered to lack the SUV39H2 gene, resulting in critical insights into the gene’s role in cellular processes and potential pathways involved in cancer and developmental biology.
The key function of these knockout cell lines lies in their ability to facilitate the exploration of gene function through loss-of-function studies. By observing the phenotypic and molecular changes that occur in the absence of the SUV39H2 gene, researchers can elucidate its contributions to epigenetic regulation and chromatin dynamics. Mechanistically, SUV39H2 promotes the methylation of lysine 9 on histone H3, a modification associated with transcriptional repression and heterochromatin formation. Investigating the consequences of knocking out this gene provides valuable insights for understanding disturbances in cellular differentiation and tumorigenesis.
From a scientific standpoint, SUVs39H2 knockout cell lines are crucial in both basic and applied research settings. They serve as pivotal models for investigating the epigenetic basis of diseases, including various forms of cancer, where alterations in chromatin regulation are common. Additionally, these cell lines can be utilized in the development of therapeutic strategies targeting epigenetic modifications.
What sets our SUV39H2 Gene Knockout Cell Lines apart from competing products is the rigorous validation and characterization process they undergo, ensuring high fidelity in gene editing and expression profiles. Our product guarantees consistency and reproducibility, enabling researchers to achieve reliable results while minimizing variability in their experiments.
For researchers and clinicians, these knockout cell lines offer an invaluable resource for advancing epigenetic research and therapeutic development. The unique capability to manipulate and study gene function in a controlled environment can significantly accelerate discoveries in genetics and cellular dynamics.
At our company, we pride ourselves on our expertise in providing high-quality biological products tailored to the needs of the research community. By continually pushing the boundaries of genetic research tools, we aim to support breakthroughs that enhance our understanding of complex biological systems.
Please note that all services are for research use only. Not intended for any clinical use.
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