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SUOX Knockout Cell Lines

Gene: SUOX

Official Full Name: sulfite oxidaseprovided by HGNC

Gene Summary: Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13638 SUOX Knockout cell line (HeLa) Human SUOX 1:3~1:6 Negative Online Inquiry
KO13639 SUOX Knockout cell line (HCT 116) Human SUOX 1:2~1:4 Negative Online Inquiry
KO13640 SUOX Knockout cell line (HEK293) Human SUOX 1:3~1:6 Negative Online Inquiry
KO13641 SUOX Knockout cell line (A549) Human SUOX 1:3~1:4 Negative Online Inquiry

Background

SUOX Gene Knockout Cell Lines are specialized cell lines engineered to disrupt the sulfite oxidase (SUOX) gene, which plays a critical role in sulfite metabolism and detoxification within the body. These cell lines enable researchers to investigate the biochemical and molecular pathways affected by SUOX deficiency, enhancing understanding of related metabolic disorders. By eliminating the SUOX gene, these cell lines effectively create a model for studying the consequences of sulfite accumulation, thereby facilitating research into therapeutic approaches for conditions such as sulfite oxidase deficiency.

The primary function of SUOX Gene Knockout Cell Lines is to serve as a tool for investigating the downstream effects of sulfite accumulation on cellular health, energy metabolism, and oxidative stress response mechanisms. This product offers researchers the ability to analyze changes in gene expression, metabolic flux, and enzymatic activity in a controlled laboratory setting, ultimately contributing to the broader understanding of various genetic and environmental factors that influence health.

In research and clinical applications, the significance of SUOX Gene Knockout Cell Lines cannot be overstated. By providing insights into sulfite-related pathophysiology, they support the development of targeted therapies and diagnostic tools for metabolic disorders. Furthermore, these cell lines can be employed in drug discovery, allowing scientists to evaluate potential compounds that could mitigate the detrimental effects of sulfite accumulation.

Compared to alternative models, SUOX Gene Knockout Cell Lines deliver a unique advantage by offering a direct and specific approach to studying SUOX-related pathways without the confounding variables present in whole-organism studies. This specificity enhances experimental reproducibility and data consistency, making them an invaluable resource for advanced biomedical research.

For researchers and clinicians focused on metabolic disorders, SUOX Gene Knockout Cell Lines provide an essential platform for innovation. Understanding the complete biological implications of SUOX deficiencies is vital for advancing therapeutic strategies that can significantly improve patient outcomes.

Our company specializes in developing cutting-edge biological products, including high-quality knockout cell lines, to empower researchers and enhance scientific exploration. With a commitment to excellence and innovation, we support the scientific community in exploring the intricacies of cellular behavior and genetic regulation.

Please note that all services are for research use only. Not intended for any clinical use.

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