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STX8 Knockout Cell Lines

Gene: STX8

Official Full Name: syntaxin 8provided by HGNC

Gene Summary: The gene is a member of the syntaxin family. The encoded protein is involved in protein trafficking from early to late endosomes via vesicle fusion and exocytosis. A related pseudogene has been identified on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00026 STX8 Knockout cell line (THP-1) Human STX8 1:2-1:4 Negative Online Inquiry
KO33202 STX8 Knockout cell line (HeLa) Human STX8 1:3~1:6 Negative Online Inquiry
KO33203 STX8 Knockout cell line (HCT 116) Human STX8 1:2~1:4 Negative Online Inquiry
KO33204 STX8 Knockout cell line (HEK293) Human STX8 1:3~1:6 Negative Online Inquiry
KO33205 STX8 Knockout cell line (A549) Human STX8 1:3~1:4 Negative Online Inquiry

Background

STX8 Gene Knockout Cell Lines are genetically engineered models in which the STX8 gene has been inactivated, providing researchers with a powerful tool for studying the biological roles and functions associated with this gene. The STX8 gene encodes a synaptosomal-associated protein that is crucial for various membrane trafficking processes within cells. In these knockout cell lines, the absence of STX8 allows for the examination of its contributions to cellular mechanisms such as exocytosis, endocytosis, and synaptic transmission, which are fundamental in neurobiology and other fields.

The primary function of these knockout lines is to facilitate the dissection of STX8's role in cellular pathways, enabling the characterization of phenotypic outcomes resultant from its loss. This is achieved through various experimental approaches, including functional assays, gene expression analyses, and imaging techniques to observe alterations in cell behavior, morphology, and signaling.

The scientific importance of STX8 Gene Knockout Cell Lines lies in their diverse applications across research and clinical settings. They serve as essential models for elucidating the pathophysiological mechanisms underlying neurological disorders and syndromic conditions. Understanding the role of STX8 in these contexts may provide insights into potential therapeutic targets for drug development.

What sets our STX8 Gene Knockout Cell Lines apart from alternatives is their precise gene editing, which ensures a complete and reproducible knockout, verified by sequencing and functional validation. This level of accuracy enhances reliability in experimental results, making them indispensable for researchers requiring rigorous validation of their hypotheses.

For researchers and clinicians alike, the availability of these specialized cell lines significantly accelerates the pace of discovery, offering a direct route to understanding complex biological systems. With our commitment to providing high-quality genetic models, our company leverages years of expertise in genetic engineering and cell biology to support cutting-edge research and innovation in the scientific community. Whether for fundamental research or translational applications, STX8 Gene Knockout Cell Lines represent a valuable asset in the pursuit of knowledge and advancements in health science.

Please note that all services are for research use only. Not intended for any clinical use.

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