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STX12 Knockout Cell Lines

Gene: STX12

Official Full Name: syntaxin 12provided by HGNC

Gene Summary: Predicted to enable SNAP receptor activity and SNARE binding activity. Involved in autophagosome assembly; cholesterol efflux; and protein stabilization. Located in several cellular components, including BLOC-1 complex; phagocytic vesicle; and phagophore assembly site. Part of SNARE complex. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28996 STX12 Knockout cell line (HeLa) Human STX12 1:3~1:6 Negative Online Inquiry
KO28997 STX12 Knockout cell line (HCT 116) Human STX12 1:2~1:4 Negative Online Inquiry
KO28998 STX12 Knockout cell line (HEK293) Human STX12 1:3~1:6 Negative Online Inquiry
KO28999 STX12 Knockout cell line (A549) Human STX12 1:3~1:4 Negative Online Inquiry

Background

STX12 Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the study of the STX12 gene, which plays a critical role in membrane trafficking and cellular communication processes. These cell lines have been meticulously modified to ensure the complete disruption of the STX12 gene, providing researchers with a robust platform to investigate the downstream effects of this gene’s absence on cellular function and pathology.

The core mechanism of the STX12 knockout involves the use of CRISPR-Cas9 technology, which ensures precise and efficient editing of the genome. By introducing disruptions in the STX12 gene, these knockout cell lines allow scientists to observe significant changes in exocytosis, endocytosis, and synaptic function. This unique mechanism facilitates in-depth research into various biological processes and diseases associated with dysregulation of intracellular trafficking, such as neurological disorders and certain cancers.

The scientific importance of STX12 Gene Knockout Cell Lines lies in their application across both basic research and clinical studies. In research settings, these models serve as valuable tools for elucidating the molecular pathways influenced by STX12, advancing our understanding of its role in pathogenesis. Clinically, insights garnered from these models can drive the development of targeted therapies aimed at correcting dysfunctional cellular processes linked to STX12.

What sets our STX12 Gene Knockout Cell Lines apart from similar products is their unparalleled specificity and reliability. Each cell line is validated for consistent performance, ensuring reproducibility of experimental results. Additionally, our commitment to quality guarantees that researchers will receive a product that is rigorously tested, providing confidence during experimentation.

For researchers and clinicians seeking to unlock the complexities of cellular machinery and develop innovative therapeutic strategies, STX12 Gene Knockout Cell Lines represent an indispensable resource. Our company prides itself on its extensive experience in creating high-quality biological products, ensuring that our customers have access to tools that enhance their scientific inquiries and drive meaningful advancements in health and medicine.

Please note that all services are for research use only. Not intended for any clinical use.

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