Gene: STON2
Official Full Name: stonin 2provided by HGNC
Gene Summary: This gene encodes a protein which is a membrane protein involved in regulating endocytotic complexes. The protein product is described as one of the clathrin-associated sorting proteins, adaptor molecules which ensure specific proteins are internalized. The encoded protein has also been shown to participate in synaptic vesicle recycling through interaction with synaptotagmin 1 required for neurotransmission. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24238 | STON2 Knockout cell line (HeLa) | Human | STON2 | 1:3~1:6 | Negative | Online Inquiry |
KO24239 | STON2 Knockout cell line (HCT 116) | Human | STON2 | 1:2~1:4 | Negative | Online Inquiry |
KO24240 | STON2 Knockout cell line (HEK293) | Human | STON2 | 1:3~1:6 | Negative | Online Inquiry |
KO24241 | STON2 Knockout cell line (A549) | Human | STON2 | 1:3~1:4 | Negative | Online Inquiry |
STON2 Gene Knockout Cell Lines are a pioneering tool in molecular biology, designed to facilitate the precise study of gene function and regulation by enabling the targeted disruption of the STON2 gene in a variety of cell types. These cell lines have been engineered using state-of-the-art CRISPR/Cas9 technology, which allows for accurate and efficient gene editing, creating a loss-of-function model that is crucial for understanding the biological role of STON2 in cellular processes such as growth, differentiation, and signal transduction.
The primary mechanism of these cell lines lies in their ability to induce double-strand breaks at the STON2 locus, followed by cellular repair processes that result in error-prone repair outcomes. This leads to the generation of mutations that effectively knock out the gene’s expression. By studying these knockout models, researchers can elucidate the impact of STON2 on various pathways and diseases, including cancer biology, neurological disorders, and developmental processes.
Most notably, the STON2 Gene Knockout Cell Lines are invaluable in both research and clinical applications. They serve as a critical resource for drug discovery and development, allowing scientists to identify potential therapeutic targets. Their relevance extends to personalized medicine, where understanding gene function is essential for tailoring treatments to individual genetic profiles.
One of the key advantages of our STON2 Gene Knockout Cell Lines is their robustness and reliability, which are validated through comprehensive genotyping and phenotypic characterization. Unlike traditional knockdown approaches, which can yield inconsistent results due to off-target effects, these knockout lines provide a definitive and stable model for researchers to study gene function.
For researchers and clinicians alike, these cell lines offer a powerful platform for advancing scientific knowledge and developing therapeutics that can improve patient outcomes. The ability to generate reproducible results efficiently further enhances their value in experimental setups.
As a leader in the field of biological products, our company is committed to providing high-quality research tools that empower scientists to push the boundaries of innovation in genetics and molecular biology. Our expertise in gene editing technologies ensures that researchers have access to the most reliable and precise models available on the market, driving progress in both academic and clinical domains.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.