Gene: STOML2
Official Full Name: stomatin like 2provided by HGNC
Gene Summary: Enables GTPase binding activity; T cell receptor binding activity; and cardiolipin binding activity. Involved in intracellular calcium ion homeostasis; mitochondrion organization; and protein complex oligomerization. Acts upstream of or within T cell receptor signaling pathway. Located in several cellular components, including immunological synapse; membrane raft; and mitochondrial envelope. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26718 | STOML2 Knockout cell line (HeLa) | Human | STOML2 | 1:3~1:6 | Negative | Online Inquiry |
KO26719 | STOML2 Knockout cell line (HCT 116) | Human | STOML2 | 1:2~1:4 | Negative | Online Inquiry |
KO26720 | STOML2 Knockout cell line (HEK293) | Human | STOML2 | 1:3~1:6 | Negative | Online Inquiry |
KO26721 | STOML2 Knockout cell line (A549) | Human | STOML2 | 1:3~1:4 | Negative | Online Inquiry |
STOML2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the Stomatin-Like 2 (STOML2) gene, facilitating a deeper understanding of its biological functions and implications in various physiological and pathological processes. Knockout cell lines are vital tools in research as they allow scientists to study the phenotypic consequences of specific gene loss, uncovering pathways and mechanisms that govern cellular behaviors.
These cell lines function by employing CRISPR-Cas9 technology, which precisely disrupts the STOML2 gene, leading to a targeted ablation of its protein product. The resultant cellular models provide a unique platform for investigating the role of STOML2 in membrane dynamics, ion transport, and cellular stress responses. Given that STOML2 has been implicated in cellular signaling and the pathophysiology of diseases such as cardiac dysfunction and neurodegenerative disorders, these cell lines are particularly important for elucidating its contribution to disease processes and identifying potential therapeutic targets.
The scientific importance of STOML2 Gene Knockout Cell Lines extends to both basic and applied research. They are invaluable for drug discovery, gene therapy development, and understanding disease mechanisms, making them instrumental in translational medicine applications. Compared to other gene editing methods, the CRISPR-Cas9 induced knockout provides higher efficiency and specificity, reducing off-target effects and enhancing the reliability of experimental outcomes.
For researchers and clinicians, utilizing STOML2 Gene Knockout Cell Lines means accessing a powerful tool for elucidating mechanisms of disease and honing in on potential pharmacological interventions with greater precision. This not only accelerates the pace of discovery but also contributes to the development of more effective therapeutic strategies.
At our company, we pride ourselves on our deep expertise in gene editing technologies and our commitment to providing high-quality biological products. Our STOML2 Gene Knockout Cell Lines are meticulously characterized and validated, ensuring that they meet the highest standards for research reliability.
Please note that all services are for research use only. Not intended for any clinical use.
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