Gene: STAMBP
Official Full Name: STAM binding proteinprovided by HGNC
Gene Summary: Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO03240 | STAMBP Knockout cell line (HeLa) | Human | STAMBP | 1:3~1:6 | Negative | Online Inquiry |
KO03241 | STAMBP Knockout cell line (HCT 116) | Human | STAMBP | 1:2~1:4 | Negative | Online Inquiry |
KO03242 | STAMBP Knockout cell line (HEK293) | Human | STAMBP | 1:3~1:6 | Negative | Online Inquiry |
KO03243 | STAMBP Knockout cell line (A549) | Human | STAMBP | 1:3~1:4 | Negative | Online Inquiry |
STAMBP Gene Knockout Cell Lines represent a sophisticated research tool developed to facilitate the study of the STAMBP gene, which is integral for cellular processes like apoptosis and inflammation. By utilizing CRISPR-Cas9 technology, these cell lines allow researchers to achieve precise inactivation of the STAMBP gene, leading to a deeper understanding of its role in various biological functions and disease states.
The primary mechanism involves the delivery of specific guide RNA designed to target the STAMBP gene, resulting in a double-strand break that, when repaired by the cell's own mechanisms, introduces a knockout mutation. This enables researchers to observe the resultant phenotypic changes, expression alterations, and molecular pathways activated in the absence of the STAMBP gene. Consequently, these cell lines serve as vital models for dissecting the role of STAMBP in critical biological pathways, including its involvement in cancer progression and neurodegenerative diseases.
In terms of scientific importance, STAMBP Gene Knockout Cell Lines hold substantial value in both basic and applied research settings. Their use is pivotal for drug screening, biomarker discovery, and the exploration of gene-environment interactions. Additionally, these cell lines have a promising potential for therapeutic applications as they can lead to the identification of novel treatment strategies targeting STAMBP-related pathways.
What sets our STAMBP Gene Knockout Cell Lines apart from alternatives is the rigorous validation and characterization our product undergoes, ensuring robustness and reproducibility in experimental results. Each cell line is developed with the utmost precision, enabling researchers to trust in their functionality and applicability to their specific research needs.
For researchers and clinicians alike, incorporating STAMBP Gene Knockout Cell Lines into their studies offers a fast track to innovative discoveries. As a pioneer in the field of gene editing and cellular models, our company is dedicated to providing high-quality biological products that empower scientific advancement and enhance therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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