Gene: ST6GALNAC5
Official Full Name: ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5provided by HGNC
Gene Summary: The protein encoded by this gene is a Golgi type II transmembrane glycosyltransferase. The encoded protein catalyzes the transfer of sialic acid to cell surface proteins to modulate cell-cell interactions. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25650 | ST6GALNAC5 Knockout cell line (HCT 116) | Human | ST6GALNAC5 | 1:2~1:4 | Negative | Online Inquiry |
ST6GALNAC5 Gene Knockout Cell Lines are genetically engineered cellular models that have had the ST6GALNAC5 gene specifically disrupted, making them invaluable tools for studying glycomic pathways and their implications in biological processes. This gene is primarily responsible for the synthesis of glycan structures that play a crucial role in cell signaling and recognition processes. By knocking out ST6GALNAC5, researchers can investigate how the absence of this gene affects glycosylation patterns, cell behavior, and interactions, ultimately deepening our understanding of glycan-mediated biological functions.
The functionality of these knockout cell lines lies in their ability to provide a controlled environment in which the consequences of ST6GALNAC5 disruption can be precisely measured. This model allows for the examination of disease mechanisms related to altered glycosylation, such as cancer progression, immune modulation, and infectious diseases caused by pathogens that exploit host glycan profiles. By elucidating these pathways, researchers can identify potential therapeutic targets for drug development.
The scientific importance of ST6GALNAC5 Gene Knockout Cell Lines extends to both fundamental research and clinical applications. In therapeutic settings, these cell models can serve as platforms for drug screening, biomarker discovery, and the development of novel treatment strategies aimed at modulating glycosylation. They also facilitate advancements in personalized medicine by correlating glycomic anomalies with patient-specific pathologies.
Compared to alternative models, ST6GALNAC5 Gene Knockout Cell Lines offer unique advantages, including the specificity of the genetic modification, reproducibility, and a clear phenotype that exposes the cellular consequences of glycosylation changes. This specificity leads to more accurate and reliable results, subsequent analyses, and interpretations.
For researchers and clinicians focused on the pivotal role of glycans in health and disease, ST6GALNAC5 Gene Knockout Cell Lines are a vital asset. They provide a robust methodology for dissecting the complexities of glycomic interactions, paving the way for breakthroughs in diagnostics and therapeutics.
Our company prides itself on its expertise in providing high-quality genetic tools tailored for advanced research. With a dedicated commitment to scientific innovation, we ensure our products meet rigorous standards for performance and reliability, empowering researchers to push the boundaries of biological understanding.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.