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ST6GALNAC5 Knockout Cell Lines

Gene: ST6GALNAC5

Official Full Name: ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5provided by HGNC

Gene Summary: The protein encoded by this gene is a Golgi type II transmembrane glycosyltransferase. The encoded protein catalyzes the transfer of sialic acid to cell surface proteins to modulate cell-cell interactions. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25650 ST6GALNAC5 Knockout cell line (HCT 116) Human ST6GALNAC5 1:2~1:4 Negative Online Inquiry

Background

ST6GALNAC5 Gene Knockout Cell Lines are genetically engineered cellular models that have had the ST6GALNAC5 gene specifically disrupted, making them invaluable tools for studying glycomic pathways and their implications in biological processes. This gene is primarily responsible for the synthesis of glycan structures that play a crucial role in cell signaling and recognition processes. By knocking out ST6GALNAC5, researchers can investigate how the absence of this gene affects glycosylation patterns, cell behavior, and interactions, ultimately deepening our understanding of glycan-mediated biological functions.

The functionality of these knockout cell lines lies in their ability to provide a controlled environment in which the consequences of ST6GALNAC5 disruption can be precisely measured. This model allows for the examination of disease mechanisms related to altered glycosylation, such as cancer progression, immune modulation, and infectious diseases caused by pathogens that exploit host glycan profiles. By elucidating these pathways, researchers can identify potential therapeutic targets for drug development.

The scientific importance of ST6GALNAC5 Gene Knockout Cell Lines extends to both fundamental research and clinical applications. In therapeutic settings, these cell models can serve as platforms for drug screening, biomarker discovery, and the development of novel treatment strategies aimed at modulating glycosylation. They also facilitate advancements in personalized medicine by correlating glycomic anomalies with patient-specific pathologies.

Compared to alternative models, ST6GALNAC5 Gene Knockout Cell Lines offer unique advantages, including the specificity of the genetic modification, reproducibility, and a clear phenotype that exposes the cellular consequences of glycosylation changes. This specificity leads to more accurate and reliable results, subsequent analyses, and interpretations.

For researchers and clinicians focused on the pivotal role of glycans in health and disease, ST6GALNAC5 Gene Knockout Cell Lines are a vital asset. They provide a robust methodology for dissecting the complexities of glycomic interactions, paving the way for breakthroughs in diagnostics and therapeutics.

Our company prides itself on its expertise in providing high-quality genetic tools tailored for advanced research. With a dedicated commitment to scientific innovation, we ensure our products meet rigorous standards for performance and reliability, empowering researchers to push the boundaries of biological understanding.

Please note that all services are for research use only. Not intended for any clinical use.

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