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SRA1 Knockout Cell Lines

Gene: SRA1

Official Full Name: steroid receptor RNA activator 1provided by HGNC

Gene Summary: Both long non-coding and protein-coding RNAs are transcribed from this gene, and they represent alternatively spliced transcript variants. This gene was initially defined as a non-coding RNA, which is a coactivator for several nuclear receptors (NRs) and is associated with breast cancer. It has now been found that this gene is involved in the regulation of many NR and non-NR activities, including metabolism, adipogenesis and chromatin organization. The long non-coding RNA transcripts interact with a variety of proteins, including the protein encoded by this gene. The encoded protein acts as a transcriptional repressor by binding to the non-coding RNA. [provided by RefSeq, Mar 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32381 SRA1 Knockout cell line (HeLa) Human SRA1 1:3~1:6 Negative Online Inquiry
KO32382 SRA1 Knockout cell line (HCT 116) Human SRA1 1:2~1:4 Negative Online Inquiry
KO32383 SRA1 Knockout cell line (HEK293) Human SRA1 1:3~1:6 Negative Online Inquiry
KO32384 SRA1 Knockout cell line (A549) Human SRA1 1:3~1:4 Negative Online Inquiry

Background

SRA1 Gene Knockout Cell Lines are specialized cellular models in which the SRA1 gene has been completely inactivated or "knocked out." This gene plays a pivotal role in various biological processes, particularly in the context of cellular differentiation and RNA metabolism, making these knockout cell lines invaluable tools for researchers exploring gene function and related pathways.

These cell lines operate on the principle of targeted gene disruption, using engineered nucleases such as CRISPR/Cas9 or RNA interference techniques to achieve precise deletion of the SRA1 gene. As a result, researchers can investigate the phenotypic changes and biochemical pathways resulting from the absence of SRA1, providing insights into its function in various cellular contexts. This mechanism serves to elucidate the role of SRA1 in pathologies, particularly in the realms of cancer biology and metabolic disorders.

The scientific importance of SRA1 Gene Knockout Cell Lines extends to their broad applications in fundamental research as well as in translational medicine. These models can be utilized for drug screening, gene therapy studies, and the development of personalized medicine approaches. Moreover, they aid in understanding the molecular underpinnings of diseases linked to SRA1 dysregulation, thus, paving the way for innovative therapeutic strategies.

Compared to alternative models, SRA1 Gene Knockout Cell Lines offer unparalleled specificity and reproducibility. While traditional methods may yield heterogeneous results or be limited by off-target effects, our meticulously developed knockout lines ensure that researchers work with high-fidelity genotypes that can be relied upon for consistent results. The ability to eliminate a single gene with precision sets these models apart, contributing to more accurate interpretations of experimental data.

The value of SRA1 Gene Knockout Cell Lines is underscored by their potential to advance our understanding of key biological processes and drive innovations in disease modeling. For researchers and clinicians, these knockout lines offer a gateway to exploring gene functions and their implications in health and disease.

At [Company Name], we pride ourselves on our expertise in developing high-quality biological products that facilitate cutting-edge research. Our commitment to scientific excellence translates into reliable solutions that empower the scientific community to unravel complex biological questions.

Please note that all services are for research use only. Not intended for any clinical use.

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