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SQOR Knockout Cell Lines

Gene: SQOR

Official Full Name: sulfide quinone oxidoreductaseprovided by HGNC

Gene Summary: The protein encoded by this gene may function in mitochondria to catalyze the conversion of sulfide to persulfides, thereby decreasing toxic concencrations of sulfide. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00611 SQOR Knockout cell line(HCT 116) Human SQOR 1:2~1:4 Negative Online Inquiry

Background

SQOR Gene Knockout Cell Lines are specialized cellular models designed to facilitate the study and manipulation of the sulfide:quinone oxidoreductase (SQOR) gene, which plays a crucial role in cellular metabolism and sulfur compounds' catabolism. Utilizing CRISPR/Cas9 gene editing technology, these cell lines feature precise deletions in the SQOR gene, allowing researchers to investigate the gene's function and its implications for various biological processes, including cellular energy production and oxidative stress responses.

The key functions of SQOR Gene Knockout Cell Lines stem from their ability to effectively simulate a loss-of-function scenario of the SQOR gene. By studying the phenotypic and molecular changes in these cell lines, scientists can elucidate the metabolic pathways involving hydrogen sulfide and assess how alterations in SQOR expression may affect overall cellular health, signaling pathways, and disease states such as cancer or neurodegenerative disorders.

The scientific importance of these knockout cell lines extends to both research and clinical applications. They serve as invaluable tools for drug discovery, allowing the identification of compounds that target metabolic abnormalities associated with SQOR dysregulation. Furthermore, the cell lines can assist in elucidating mechanisms behind drug resistance or susceptibility to certain therapies in cancer research.

Compared to traditional methods or whole-organism models, SQOR Gene Knockout Cell Lines offer distinct advantages: they enable high-throughput screening, provide a controlled environment for gene function analysis, and reduce variability typically associated with in vivo studies. Their specificity for the SQOR gene allows for streamlined experimentation, increasing the reliability and reproducibility of results.

For researchers and clinicians focused on metabolic disorders, drug development, or gene function studies, the SQOR Gene Knockout Cell Lines represent a cutting-edge resource that promises to enhance scientific understanding and therapeutic strategies. Our company specializes in providing high-quality biological products, ensuring that every cell line is rigorously validated and accompanied by comprehensive technical support for optimal research outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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