Gene: SPR
Official Full Name: sepiapterin reductaseprovided by HGNC
Gene Summary: This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO35261 | SPR Knockout cell line (HeLa) | Human | SPR | 1:3~1:6 | Negative | Online Inquiry |
KO35262 | SPR Knockout cell line (HCT 116) | Human | SPR | 1:2~1:4 | Negative | Online Inquiry |
KO35263 | SPR Knockout cell line (HEK293) | Human | SPR | 1:3~1:6 | Negative | Online Inquiry |
KO35264 | SPR Knockout cell line (A549) | Human | SPR | 1:3~1:4 | Negative | Online Inquiry |
SPR Gene Knockout Cell Lines are advanced biological tools designed to facilitate the study of gene function in a controlled laboratory setting. These cell lines are generated using sophisticated CRISPR-Cas9 gene-editing technology, which allows for precise and efficient disruption of specific genes. The targeted knockouts in these cell lines provide invaluable insights into cellular mechanisms, enabling researchers to investigate the role of individual genes in various biological processes, such as disease progression, development, and cellular signaling pathways.
The key function of SPR Gene Knockout Cell Lines lies in their ability to allow scientists to examine the phenotypic consequences of gene disruption. Once a specific gene is knocked out, researchers can observe resultant characteristics, such as changes in cell proliferation, differentiation, or response to therapies. This approach has become pivotal in fields such as cancer research, drug development, and functional genomics.
The scientific importance of these cell lines is particularly evident in both research and clinical settings. They serve as powerful models for understanding genetic diseases, enabling the identification of potential therapeutic targets. In addition, SPR Gene Knockout Cell Lines can be utilized in pharmaceutical research to evaluate drug efficacy and safety by observing altered cellular responses linked to gene deletions.
One of the notable advantages of SPR Gene Knockout Cell Lines is their specificity and reproducibility. Unlike traditional methods that may yield inconsistent results or involve time-consuming processes, the precision of CRISPR technology ensures that researchers can generate stable cell lines that consistently exhibit the desired gene knockout phenotype. Furthermore, our extensive collection encompasses a wide variety of cell types, making it easier for researchers to select the model most relevant to their specific study.
For researchers and clinicians alike, SPR Gene Knockout Cell Lines represent an invaluable asset in the quest for new discoveries. The depth of information gained from these models can significantly accelerate advancements in personalized medicine and enhance our understanding of genetic contributions to health and disease. Our company, with a strong commitment to innovation and excellence in biological research products, is proud to offer these cutting-edge tools that empower our clients to push the boundaries of scientific inquiry.
Please note that all services are for research use only. Not intended for any clinical use.
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