Gene: SPNS1
Official Full Name: SPNS lysolipid transporter 1, lysophospholipidprovided by HGNC
Gene Summary: Predicted to enable transmembrane transporter activity. Predicted to be involved in lysophospholipid transport and phospholipid efflux. Predicted to act upstream of or within regulation of lysosomal lumen pH. Located in lysosomal membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00329 | SPNS1 Knockout cell line (HeLa) | Human | SPNS1 | 1:3~1:6 | Negative | Online Inquiry |
KO25277 | SPNS1 Knockout cell line (HCT 116) | Human | SPNS1 | 1:2~1:4 | Negative | Online Inquiry |
KO25278 | SPNS1 Knockout cell line (HEK293) | Human | SPNS1 | 1:3~1:6 | Negative | Online Inquiry |
KO25279 | SPNS1 Knockout cell line (A549) | Human | SPNS1 | 1:3~1:4 | Negative | Online Inquiry |
SPNS1 Gene Knockout Cell Lines are specifically engineered cellular models in which the Sphingomyelin Phosphodiesterase 1 (SPNS1) gene has been selectively inactivated. These advanced cell lines are essential tools for investigating the role of SPNS1 in various biological processes and diseases, particularly in lipid metabolism, immune responses, and cellular signaling pathways.
The primary function of these knockout cell lines is to facilitate the exploration of SPNS1's contribution to cellular physiology and its involvement in pathophysiological conditions. By studying these cells, researchers can decipher the gene's role in sphingolipid transport and its interaction with other intracellular signaling molecules. The knockout mechanism effectively disrupts normal gene expression, allowing for precise examinations of cellular changes and the compensatory mechanisms that may arise in its absence, thereby shedding light on the SPNS1 gene's functional significance.
The scientific importance of SPNS1 Gene Knockout Cell Lines is profound, particularly in research focused on diseases such as cancer, neurodegenerative disorders, and metabolic syndromes. Clinical applications could include the development of targeted therapies that modulate SPNS1 activity, potentially opening new avenues for treatment based on a better understanding of its biological roles.
When compared to conventional wild-type cell lines or other gene-editing techniques, SPNS1 Gene Knockout Cell Lines offer the unique advantage of definitive gene disruption, enabling clearer results and insights. Researchers will find these cell lines invaluable for experimental reproducibility and reliability in revealing gene function, thus propelling translational research forward.
By choosing SPNS1 Gene Knockout Cell Lines, researchers and clinicians can be confident in their ability to conduct high-quality, impactful science. Our company specializes in delivering expertly crafted biological products, leveraging cutting-edge gene-editing technologies to support the scientific community's commitment to innovation and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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