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SPATA33 Knockout Cell Lines

Gene: SPATA33

Official Full Name: spermatogenesis associated 33provided by HGNC

Gene Summary: Predicted to be involved in mitophagy. Predicted to act upstream of or within fertilization; flagellated sperm motility; and protein localization. Predicted to be located in male germ cell nucleus and sperm mitochondrial sheath. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28265 SPATA33 Knockout cell line (HeLa) Human SPATA33 1:3~1:6 Negative Online Inquiry
KO28266 SPATA33 Knockout cell line (HCT 116) Human SPATA33 1:2~1:4 Negative Online Inquiry
KO28267 SPATA33 Knockout cell line (HEK293) Human SPATA33 1:3~1:6 Negative Online Inquiry
KO28268 SPATA33 Knockout cell line (A549) Human SPATA33 1:3~1:4 Negative Online Inquiry

Background

SPATA33 Gene Knockout Cell Lines are specialized cellular models engineered to lack the SPATA33 gene, which encodes a protein implicated in various cellular processes, including gametogenesis and spermatogenesis. These knockout cell lines serve as a critical research tool to elucidate the role of SPATA33 in human biology, particularly in reproductive health and related disorders.

The primary function of these knockout cell lines is to provide researchers with a reliable platform for studying the downstream effects of SPATA33 deficiency, elucidating its contribution to cell proliferation, differentiation, and apoptosis. By using CRISPR-Cas9 technology, the SPATA33 gene has been effectively disrupted, allowing for the examination of phenotypic changes and molecular mechanisms related to its absence. This approach enables researchers to explore cellular pathways that may be involved in fertility issues or developmental abnormalities.

The scientific relevance of SPATA33 Gene Knockout Cell Lines extends to both foundational research and potential clinical applications. They facilitate the study of genetic and epigenetic factors influencing male infertility, making them invaluable for investigators focusing on reproductive technologies and genetic counseling. Moreover, these cell lines can be employed in drug screening assays to identify therapeutic targets or pathways that could ameliorate reproductive health problems.

What sets SPATA33 Gene Knockout Cell Lines apart from other genetic models is their high fidelity and reproducibility. They are derived from well-characterized genetic backgrounds, ensuring that experimental outcomes are consistent and reliable. Furthermore, their use reduces the ethical concerns associated with animal models, allowing for more efficient and humane research practices.

For researchers and clinicians, the value of SPATA33 Gene Knockout Cell Lines lies in their ability to enhance understanding of gene function and its implications in health and disease. Our company specializes in the development and optimization of advanced cellular models, employing cutting-edge technologies to meet the needs of the scientific community. By providing these precisely engineered cell lines, we empower researchers to drive innovation in reproductive biology and therapeutic discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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