Gene: SPANXC
Official Full Name: SPANX family member Cprovided by HGNC
Gene Summary: Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13826 | SPANXC Knockout cell line (A549) | Human | SPANXC | 1:3~1:4 | Negative | Online Inquiry |
SPANXC Gene Knockout Cell Lines are cutting-edge, genetically engineered cellular models designed to precisely eliminate the expression of specific genes in diverse mammalian cell types. Utilizing targeted CRISPR-Cas9 technology, these cell lines allow researchers to create knockout mutations that enable in-depth functional analyses of gene function, biochemical pathways, and disease mechanisms. By silencing unwanted gene expression, SPANXC cell lines facilitate more accurate modeling of physiological conditions, thus paving the way for breakthroughs in biomedical research.
The key mechanism underlying the SPANXC cell lines is the use of CRISPR-Cas9 gene editing, which allows for high specificity and efficiency in creating deliberate genomic disruptions. This precision ensures that off-target effects are minimized, providing confidence in experimental results. These knockout models can be easily cultured and propagated, simplifying the experimental workflow for researchers.
The scientific importance of SPANXC Gene Knockout Cell Lines is profound, offering transformative applications in various fields such as cancer research, developmental biology, and pharmacogenomics. By elucidating gene function, they aid in the identification of new therapeutic targets and the understanding of genetic disorders, thereby contributing to the advancement of personalized medicine.
Among their unique selling points, SPANXC cell lines provide unparalleled reliability, as they are rigorously validated through extensive characterization and quality control processes. Compared to traditional knockout models, SPANXC cell lines exhibit enhanced efficiency and reproducibility, which are crucial for producing reliable data in research settings.
Researchers and clinicians will find SPANXC Gene Knockout Cell Lines valuable due to their ability to accelerate experimental timelines, reduce resource expenditure, and elevate the quality of scientific investigations. Our commitment to innovation and excellence in biological products positions our company as a leader in the field, ensuring that we provide the tools necessary to drive your research endeavors forward.
Please note that all services are for research use only. Not intended for any clinical use.
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