Home / SPANXB1 Knockout Cell Lines

SPANXB1 Knockout Cell Lines

Gene: SPANXB1

Official Full Name: SPANX family member B1provided by HGNC

Gene Summary: Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes, which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular family member contains an additional 18 nucleotides in its coding region compared to the other family members in the same gene cluster. This family member is also subject to gene copy number variation. Although the protein encoded by this gene contains consensus nuclear localization signals, the major site for subcellular localization of expressed protein is in the cytoplasmic droplets of ejaculated spermatozoa. This protein provides a biochemical marker for studying the unique structures in spermatazoa, while attempting to further define its role in spermatogenesis. [provided by RefSeq, Apr 2014]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13827 SPANXB1 Knockout cell line (A549) Human SPANXB1 1:3~1:4 Negative Online Inquiry

Background

SPANXB1 Gene Knockout Cell Lines represent a novel tool in the field of molecular biology, specifically designed to facilitate the study of gene function and regulatory mechanisms associated with the SPANXB1 gene. These cell lines have been engineered using CRISPR/Cas9 technology to create precise deletions within the SPANXB1 gene, enabling researchers to investigate the physiological roles and potential pathological contributions of this gene in various biological contexts.

The key function of these knockout cell lines lies in their ability to provide a controlled environment where the SPANXB1 gene is entirely absent, allowing for the examination of phenotypic changes that occur as a result of its loss. This system is instrumental in understanding mechanisms related to cellular processes such as differentiation, proliferation, and stress response, as well as examining the gene’s involvement in disease pathways and potential therapeutic targets.

In research and clinical settings, the SPANXB1 gene has garnered attention due to its potential implications in cancer biology and reproductive health. By utilizing these knockout cell lines, scientists can dissect the contributions of SPANXB1 in tumorigenesis or assess its role in gametogenesis and early embryonic development, paving the way for breakthroughs in both fundamental biology and translational research.

One of the significant advantages of the SPANXB1 Gene Knockout Cell Lines is their reliability and reproducibility, which are critical for obtaining consistent experimental results. Compared to alternative gene editing models, these cell lines offer a more stable genetic background, enabling precise control over experimental conditions and thereby minimizing variability.

For researchers and clinicians, these knockout cell lines are invaluable resources that not only enhance the understanding of the SPANXB1 gene but also facilitate the exploration of innovative therapeutic strategies. Our company specializes in the development of high-quality genetic tools, ensuring that every product, including the SPANXB1 Gene Knockout Cell Lines, is rigorously validated and optimized for peak performance in scientific research. With our commitment to excellence, we empower the scientific community to push the boundaries of discovery.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.