Gene: SNX14
Official Full Name: sorting nexin 14provided by HGNC
Gene Summary: This gene encodes a member of the sorting nexin family. Members of this family have a phox (PX) phosphoinositide binding domain and are involved in intracellular trafficking. The encoded protein also contains a regulator of G protein signaling (RGS) domain. Regulator of G protein signaling family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. Alternate splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO13862 | SNX14 Knockout cell line (HeLa) | Human | SNX14 | 1:3~1:6 | Negative | Online Inquiry |
KO13863 | SNX14 Knockout cell line (HCT 116) | Human | SNX14 | 1:2~1:4 | Negative | Online Inquiry |
KO13864 | SNX14 Knockout cell line (HEK293) | Human | SNX14 | 1:3~1:6 | Negative | Online Inquiry |
KO13865 | SNX14 Knockout cell line (A549) | Human | SNX14 | 1:3~1:4 | Negative | Online Inquiry |
SNX14 Gene Knockout Cell Lines refer to genetically engineered cell lines in which the SNX14 gene has been specifically disrupted or knocked out. This technique is pivotal for understanding gene function and the biological pathways in which SNX14 is involved. SNX14, a member of the sorting nexins family, is implicated in diverse cellular processes, including endosomal trafficking and cellular response to stress. By studying these knockout cell lines, researchers can elucidate the role of SNX14 in various physiological contexts and disease states.
The key mechanism underlying the functionality of SNX14 knockout cell lines lies in their ability to serve as a powerful model to investigate its absence's effects on cellular mechanisms. This facilitates in-depth studies of processes like vesicle trafficking, protein sorting, and cellular signaling pathways affected by SNX14. In both basic research and translational studies, these cell lines are crucial for identifying potential therapeutic targets for diseases linked to cellular transport dysfunctions.
The scientific importance of SNX14 Gene Knockout Cell Lines cannot be overstated. They are invaluable in research settings aiming to explore neurological disorders, as mutations and dysfunction in SNX14 have been associated with conditions such as intellectual disabilities and other neurodevelopmental disorders. Moreover, these cell lines provide an essential tool for drug discovery, enabling the identification of new compounds and therapeutic strategies aimed at modulating the specific pathways influenced by SNX14.
One of the most significant advantages of using our SNX14 knockout cell lines is their robust and reproducible nature, backed by precise genome editing techniques such as CRISPR-Cas9. Unlike other gene disruption methods, our product ensures a complete knockout without off-target effects, providing high specificity that is critical for experimental accuracy. This enhances confidence in experimental outcomes and fosters a deeper understanding of the underlying biology.
Researchers and clinicians seeking to unravel complex cellular mechanisms or develop novel therapeutic interventions will find SNX14 Gene Knockout Cell Lines invaluable. The ability to study the function of this gene in a controlled environment allows for the exploration of innovative research avenues that can lead to breakthrough treatments.
Our company specializes in providing high-quality biological products, driven by a commitment to excellence in genetic engineering and cell line development. We are dedicated to supporting the research community with precise, reliable tools that enhance scientific discovery and clinical innovation.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.