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SMIM15 Knockout Cell Lines

Gene: SMIM15

Official Full Name: small integral membrane protein 15provided by HGNC

Gene Summary: Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13922 SMIM15 Knockout cell line (HeLa) Human SMIM15 1:3~1:6 Negative Online Inquiry
KO13923 SMIM15 Knockout cell line (HCT 116) Human SMIM15 1:2~1:4 Negative Online Inquiry
KO13924 SMIM15 Knockout cell line (HEK293) Human SMIM15 1:3~1:6 Negative Online Inquiry
KO13925 SMIM15 Knockout cell line (A549) Human SMIM15 1:3~1:4 Negative Online Inquiry

Background

SMIM15 Gene Knockout Cell Lines are highly specialized cell models engineered to functionally inactivate the SMIM15 gene, which encodes for a protein implicated in various biological processes, including cellular proliferation, differentiation, and immune modulation. By utilizing CRISPR-Cas9 gene editing technology, these cell lines provide researchers with a potent tool to elucidate the specific roles of SMIM15 within cellular systems, enabling the dissection of its contribution to pathophysiological states.

The key mechanism of how these cell lines operate lies in the targeted deletion of the SMIM15 gene. This results in a loss of gene function, permitting comprehensive analysis of the downstream effects on cell behavior and signaling pathways. Researchers can observe alterations in cell morphology, growth rates, and expression profiles of other key genes, thereby providing insights into the physiological implications of SMIM15 in various contexts, including cancer research and immunology.

In the scientific realm, these knockout cell lines are invaluable for understanding gene function and interaction networks. Their applications span across both basic research and clinical studies, where they serve as models for disease or therapeutic response. For instance, researchers investigating novel therapeutic approaches can utilize these models to evaluate the implications of restoring SMIM15 function or blocking its pathways.

Compared to traditional cell lines, SMIM15 Gene Knockout Cell Lines offer significant advantages such as greater specificity in gene targeting and the ability to predict the in vivo behavior of SMIM15-deficient cells, which conventional approaches may not achieve effectively. This specificity not only enhances reproducibility in experimental results but also minimizes the potential for off-target effects that can confound experimental outcomes.

For researchers and clinicians, the value of these cell lines is underscored by their potential to advance knowledge in gene function and disease mechanisms, thereby informing the development of targeted therapies and personalized medicine strategies. Utilizing SMIM15 Gene Knockout Cell Lines means gaining access to cutting-edge tools that can substantially accelerate the pace of discovery in biological research.

Our company's expertise in genetic engineering and cell line development ensures that our SMIM15 Gene Knockout Cell Lines meet the highest standards of quality and functionality, supporting researchers in their quest for groundbreaking discoveries. We are committed to providing innovative biological solutions that empower the scientific community to explore and understand the complexities of life at the cellular level.

Please note that all services are for research use only. Not intended for any clinical use.

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