Gene: SMCHD1
Official Full Name: structural maintenance of chromosomes flexible hinge domain containing 1provided by HGNC
Gene Summary: This gene encodes a protein which contains a hinge region domain found in members of the SMC (structural maintenance of chromosomes) protein family. [provided by RefSeq, Dec 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29409 | SMCHD1 Knockout cell line (HeLa) | Human | SMCHD1 | 1:3~1:6 | Negative | Online Inquiry |
KO29410 | SMCHD1 Knockout cell line (HCT 116) | Human | SMCHD1 | 1:2~1:4 | Negative | Online Inquiry |
KO29411 | SMCHD1 Knockout cell line (HEK293) | Human | SMCHD1 | 1:3~1:6 | Negative | Online Inquiry |
KO29412 | SMCHD1 Knockout cell line (A549) | Human | SMCHD1 | 1:3~1:4 | Negative | Online Inquiry |
SMCHD1 Gene Knockout Cell Lines are advanced biological tools engineered to facilitate the study of SMCHD1 (Structural Maintenance of Chromosomes Flexible Hinge Domain 1), an essential gene implicated in chromatin structure regulation and genomic imprinting. These knockout cell lines, developed through precise CRISPR-Cas9 gene-editing technology, allow researchers to investigate the functional implications of SMCHD1 deficiency in various cellular contexts, enabling a deeper understanding of its role in developmental biology and disease mechanisms.
The primary function of SMCHD1 involves the organization of chromatin architecture, which is essential for the proper expression of imprinted genes. By utilizing these knockout cell lines, researchers can observe the effects of SMCHD1 ablation on gene expression profiles, chromatin accessibility, and cellular differentiation processes. This model is particularly valuable for studying diseases linked to chromatin dysregulation, such as certain cancers and developmental disorders.
The scientific significance of SMCHD1 Gene Knockout Cell Lines lies in their versatility for both basic research and therapeutic investigations. Their application spans across various fields, including epigenetics, oncology, and developmental biology, making them indispensable for understanding complex genetic interactions and pathways. Compared to alternative models, these cell lines provide an unparalleled degree of specificity and control over genetic variability, allowing for robust, reproducible results.
Moreover, the unique selling propositions of SMCHD1 Gene Knockout Cell Lines include their ease of use and compatibility with high-throughput screening, making them an efficient choice for laboratories looking to maximize productivity while ensuring high fidelity in experimental outcomes. Researchers are increasingly recognizing the potential of these knockout models to provide insights into the molecular underpinnings of health and disease.
Our company prides itself on being at the forefront of genetic research tools, dedicated to delivering high-quality biological products that empower scientists and clinicians alike. With a commitment to advancing scientific discovery, we ensure our offerings meet rigorous standards of excellence, enabling users to perform groundbreaking research with confidence.
Please note that all services are for research use only. Not intended for any clinical use.
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