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SLC45A1 Knockout Cell Lines

Gene: SLC45A1

Official Full Name: solute carrier family 45 member 1provided by HGNC

Gene Summary: This gene was isolated initially from a region on chromosome 1p that is frequently deleted in human neuroblastoma, although no causal relationship has since been demonstrated. The encoded protein belongs to the glycoside-pentoside-hexuronide cation symporter transporter family and may play a role in glucose uptake. [provided by RefSeq, Mar 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23336 SLC45A1 Knockout cell line (HCT 116) Human SLC45A1 1:2~1:4 Negative Online Inquiry
KO23337 SLC45A1 Knockout cell line (A549) Human SLC45A1 1:3~1:4 Negative Online Inquiry

Background

SLC45A1 Gene Knockout Cell Lines are genetically engineered cellular models where the SLC45A1 gene has been systematically inactivated. This gene encodes a membrane transporter protein that plays a critical role in various physiological processes, including the transport of small molecules and ions across cellular membranes. By utilizing CRISPR/Cas9 technology, these cell lines allow researchers to investigate the functional consequences of SLC45A1 loss, offering valuable insights into its role in metabolic pathways and cellular homeostasis.

The primary mechanisms at play in SLC45A1 Gene Knockout Cell Lines involve the disruption of normal protein functions attributable to the SLC45A1 gene. This genetic modification facilitates the exploration of altered physiological responses in cellular environments, including changes in nutrient uptake, osmotic balance, and cell signaling pathways. Researchers can utilize these cell lines to model conditions associated with SLC45A1 dysregulation, such as certain metabolic disorders and cancer, thereby establishing a foundation for the discovery of therapeutic targets or intervention strategies.

The scientific importance of SLC45A1 Gene Knockout Cell Lines cannot be overstated, as they serve as an essential tool for both basic and applied research. These cell lines are particularly relevant for explorations in pharmacogenomics, toxicology, and drug development, where understanding the interaction between genetic variations and drug response is crucial. Compared to traditional methods such as pharmacological inhibition or knockdown approaches, gene knockout provides a more definitive and stable means of studying gene function, enhancing the reliability of experimental outcomes.

What sets our SLC45A1 Gene Knockout Cell Lines apart from alternatives is their validated performance in diverse experimental contexts, coupled with the robust documentation supporting their characteristics and usage. Researchers, clinicians, and biopharmaceutical companies will find this product invaluable for investigating genotype-phenotype relationships and to foster innovations in precision medicine.

Our company specializes in the development and distribution of high-quality genetic tools and models, ensuring that our customers have access to state-of-the-art products that support their groundbreaking research and clinical endeavors. Trust in our expertise and commitment to excellence as you explore the potential of SLC45A1 Gene Knockout Cell Lines for your research initiatives.

Please note that all services are for research use only. Not intended for any clinical use.

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