Home / SLC35D2 Knockout Cell Lines

SLC35D2 Knockout Cell Lines

Gene: SLC35D2

Official Full Name: solute carrier family 35 member D2provided by HGNC

Gene Summary: Nucleotide sugars, which are synthesized in the cytosol or the nucleus, are high-energy donor substrates for glycosyltransferases located in the lumen of the endoplasmic reticulum and Golgi apparatus. Translocation of nucleotide sugars from the cytosol into the lumen compartment is mediated by specific nucleotide sugar transporters, such as SLC35D2 (Suda et al., 2004 [PubMed 15082721]).[supplied by OMIM, Mar 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO31283 SLC35D2 Knockout cell line (HeLa) Human SLC35D2 1:3~1:6 Negative Online Inquiry
KO31284 SLC35D2 Knockout cell line (HCT 116) Human SLC35D2 1:2~1:4 Negative Online Inquiry
KO31285 SLC35D2 Knockout cell line (HEK293) Human SLC35D2 1:3~1:6 Negative Online Inquiry
KO31286 SLC35D2 Knockout cell line (A549) Human SLC35D2 1:3~1:4 Negative Online Inquiry

Background

SLC35D2 Gene Knockout Cell Lines are specially designed cellular models in which the SLC35D2 gene has been functionally disrupted, allowing for the investigation of its biological role in various physiological processes. SLC35D2 encodes a nucleotide-sugar transporter that is integral to the glycosylation pathways, which are critical for protein folding, function, and cellular communication. By knocking out this gene, researchers can observe the resultant changes in glycosylation patterns, providing insights into its impact on cell signaling, immune response, and disease pathology.

These cell lines function as powerful tools in dissecting the role of SLC35D2 in cellular mechanisms and translating these findings to therapeutic strategies. For instance, they can be employed to study the effects of altered glycosylation in conditions such as cancer, where aberrant glycosylation patterns are common. Moreover, SLC35D2 Gene Knockout Cell Lines can aid in drug discovery efforts by serving as a platform to screen compounds targeting glycosylation processes.

One of the main advantages of using SLC35D2 Knockout models over traditional methods is their specificity and reproducibility. Standard techniques such as CRISPR/Cas9 have been employed to ensure precise gene editing, minimizing off-target effects that can confound results. Additionally, these cell lines are readily available and easy to use, facilitating rapid experimental turnaround compared to other more complex systems.

The value of SLC35D2 Gene Knockout Cell Lines is underpinned by their potential to unlock new avenues of research in glycosylation and its implications in health and disease. Researchers and clinicians seeking to enhance their studies on cellular mechanisms or to explore novel therapeutic approaches will find these cell lines to be indispensable.

Our company specializes in providing high-quality biological products, including gene knockout cell lines, developed through rigorous validation processes and backed by comprehensive support services. Our expertise in molecular biology ensures that you receive reliable, cutting-edge tools to advance your research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.