SLC31A2 Knockout Cell Lines

SLC31A2 Gene Knockout Cell Lines are genetically modified human cell lines in which the SLC31A2 gene, responsible for encoding the copper transporter protein Ctr2, has been selectively disrupted. This knockout approach enables researchers to study the role of SLC31A2 in cellular copper homeostasis, transport mechanisms, and its broader implications in conditions such as Wilson’s disease and neurodegeneration. The disruption of this gene alters the normal functioning of copper uptake, allowing for a clearer understanding of its physiological roles and potential pathological consequences.

The key function of these cell lines lies in their ability to mimic the effects of SLC31A2 deficiency. By utilizing CRISPR-Cas9 technology, the knockout process ensures precise gene editing with high efficiency, resulting in substantial variations in copper accumulation and related signaling pathways. Researchers can investigate the downstream effects of altered copper levels on cellular proliferation, differentiation, and apoptosis, thus providing insights into disease mechanisms.

Scientifically, SLC31A2 Gene Knockout Cell Lines hold significant importance as they serve as a powerful tool for investigating the nuances of copper transport related to various disorders. Their applications extend into pharmacological research, where scientists can screen for compounds that modulate copper levels and explore therapeutic interventions.

The unique advantage of utilizing our SLC31A2 knockout cell lines stems from their verified genomic integrity, characterized stability, and reproducibility in experimental settings. Unlike other models, our cell lines provide a more accurate reflection of human physiology, ensuring that research findings can be translated more effectively into clinical practice.

For researchers and clinicians seeking to advance their understanding of copper's role in biological systems, these cell lines represent an invaluable resource. Moreover, our company prides itself on having a dedicated team of molecular biologists and cell culturists who ensure that each product meets the highest standards of quality and efficacy. By choosing our products, users gain access to unparalleled support and expertise in the realm of genetic research.