Gene: SLC27A4
Official Full Name: solute carrier family 27 member 4provided by HGNC
Gene Summary: This gene encodes a member of a family of fatty acid transport proteins, which are involved in translocation of long-chain fatty acids cross the plasma membrane. This protein is expressed at high levels on the apical side of mature enterocytes in the small intestine, and appears to be the principal fatty acid transporter in enterocytes. Clinical studies suggest this gene as a candidate gene for the insulin resistance syndrome. Mutations in this gene have been associated with ichthyosis prematurity syndrome. [provided by RefSeq, Apr 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO03950 | SLC27A4 Knockout cell line (HeLa) | Human | SLC27A4 | 1:3~1:6 | Negative | Online Inquiry |
KO03951 | SLC27A4 Knockout cell line (HCT 116) | Human | SLC27A4 | 1:2~1:4 | Negative | Online Inquiry |
KO03952 | SLC27A4 Knockout cell line (HEK293) | Human | SLC27A4 | 1:3~1:6 | Negative | Online Inquiry |
KO03953 | SLC27A4 Knockout cell line (A549) | Human | SLC27A4 | 1:3~1:4 | Negative | Online Inquiry |
SLC27A4 Gene Knockout Cell Lines are genetically engineered cell models designed to study the function and implications of the SLC27A4 gene, which encodes for the solute carrier family 27 member 4 protein. This protein plays a critical role in the transport of long-chain fatty acids across cellular membranes, influencing various metabolic processes and cellular functions. The knockout cell lines enable researchers to precisely investigate the consequences of SLC27A4 gene deletion, aiding in the elucidation of pathways involved in lipid metabolism, energy regulation, and cellular signaling.
These cell lines operate by employing CRISPR-Cas9 gene-editing technology, ensuring a reliable and specific deletion of the SLC27A4 gene. Researchers can utilize these models to explore the downstream effects on lipid uptake and metabolism, contributing significantly to our understanding of disorders associated with fatty acid transport, such as obesity, diabetes, and cardiovascular diseases.
The scientific importance of SLC27A4 gene knockout cell lines is vast, providing essential insights for both basic and applied research in fields ranging from metabolic diseases to pharmacology. In clinical settings, this product is invaluable for developing targeted therapies aimed at metabolic disorders or for investigating drug effects on lipid metabolism.
Compared to traditional models, SLC27A4 gene knockout cell lines offer unparalleled specificity and reproducibility, eliminating background variability associated with non-targeted models. Their unique ability to replicate specific metabolic conditions positions them as a superior choice for researchers seeking reliable data on SLC27A4 gene functions.
In conclusion, SLC27A4 Gene Knockout Cell Lines represent a critical tool in advancing our understanding of metabolic diseases and developing innovative therapeutic strategies. Supported by our company’s expertise in gene-editing technologies and a commitment to providing high-quality biological products, we empower researchers and clinicians with the tools necessary to drive significant scientific discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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