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SLC25A39 Knockout Cell Lines

Gene: SLC25A39

Official Full Name: solute carrier family 25 member 39provided by HGNC

Gene Summary: This gene encodes a member of the SLC25 transporter or mitochondrial carrier family of proteins. Members of this family are encoded by the nuclear genome while their protein products are usually embedded in the inner mitochondrial membrane and exhibit wide-ranging substrate specificity. Although the encoded protein is currently considered an orphan transporter, this protein is related to other carriers known to transport amino acids. This protein may play a role in iron homeostasis. [provided by RefSeq, Mar 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02045 SLC25A39 Knockout cell line (HeLa) Human SLC25A39 1:3~1:6 Negative Online Inquiry
KO02046 SLC25A39 Knockout cell line (HCT 116) Human SLC25A39 1:2~1:4 Negative Online Inquiry
KO02047 SLC25A39 Knockout cell line (HEK293) Human SLC25A39 1:3~1:6 Negative Online Inquiry
KO02048 SLC25A39 Knockout cell line (A549) Human SLC25A39 1:3~1:4 Negative Online Inquiry

Background

SLC25A39 Gene Knockout Cell Lines are genetically engineered cellular models designed to facilitate the study of the SLC25A39 gene's role within cellular metabolism and mitochondrial function. This product provides researchers with a valuable tool to investigate gene function through the creation of knockout models that specifically lack the SLC25A39 gene. By employing CRISPR/Cas9 gene-editing technology, these cell lines exhibit a complete absence of SLC25A39 expression, allowing for the evaluation of the gene's contributions to critical pathways, such as energy production and intermediary metabolism.

The primary functions of the SLC25A39 gene involve encoding a mitochondrial carrier protein implicated in the transport of key metabolites across the mitochondrial membrane. In particular, the gene is associated with the transport of nucleotides and other essential molecules, which play crucial roles in cellular bioenergetics and signaling. Utilizing these knockout cell lines, researchers can elucidate the biochemical pathways affected by the loss of SLC25A39, potentially revealing novel therapeutic targets for metabolic disorders.

The scientific importance of these cell lines extends to multiple fields, including molecular biology, biochemistry, and medical research. They serve as critical experimental models to study mitochondrial diseases, explore the effects of gene loss on cellular physiology, and assess the impact of therapeutic interventions aimed at restoring normal function.

Compared to other alternatives, such as chemically-induced knockouts or transient knockdown approaches, SLC25A39 Gene Knockout Cell Lines provide a more stable and reproducible model for long-term studies. These cell lines maintain genetic fidelity and can be readily expanded for extensive research applications, ensuring consistent results and reliability.

Researchers and clinicians will find significant value in these knockout cell lines as they provide a unique opportunity to dissect gene function within the context of mitochondrial health, thereby advancing knowledge in metabolic regulation and its implications in disease. Furthermore, our company's long-standing expertise in genetic engineering and commitment to providing high-quality biological products ensure that these cell lines are validated for performance and reliability, making them an indispensable asset in advanced biological research.

Please note that all services are for research use only. Not intended for any clinical use.

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