Gene: SLC25A38
Official Full Name: solute carrier family 25 member 38provided by HGNC
Gene Summary: This gene is a member of the mitochondrial carrier family. The encoded protein is required during erythropoiesis and is important for the biosynthesis of heme. Mutations in this gene are the cause of autosomal congenital sideroblastic anemia (anemia, sideroblastic, 2, pyridoxine-refractory). A related pseudogene is found on chromosome 1. [provided by RefSeq, Aug 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
GP00552 | SLC25A38 gRNA1-gRNA2 KO plasmid | SLC25A38 | $850 | |||
KO01412 | SLC25A38 Knockout cell line(ZR75-1) | Human | SLC25A38 | Negative | Online Inquiry | |
KO14061 | SLC25A38 Knockout cell line (HeLa) | Human | SLC25A38 | 1:3~1:6 | Negative | Online Inquiry |
KO14062 | SLC25A38 Knockout cell line (HCT 116) | Human | SLC25A38 | 1:2~1:4 | Negative | Online Inquiry |
KO14063 | SLC25A38 Knockout cell line (HEK293) | Human | SLC25A38 | 1:3~1:6 | Negative | Online Inquiry |
KO14064 | SLC25A38 Knockout cell line (A549) | Human | SLC25A38 | 1:3~1:4 | Negative | Online Inquiry |
SLC25A38 Gene Knockout Cell Lines are genetically engineered cell lines that have had the SLC25A38 gene inactivated, leading to a disruption in its normal function. The SLC25A38 gene encodes a mitochondrial carrier protein that plays a critical role in the transport of metabolites across the mitochondrial inner membrane, particularly in the context of heme and glycine metabolism. By utilizing these knockout cell lines, researchers can elucidate the gene’s role in various metabolic pathways and disease states, providing valuable insights into cellular functions and dysfunctions.
The primary function of SLC25A38 involves the regulation of mitochondrial processes essential for energy metabolism. By studying the knockout variants, researchers can observe the resultant phenotypic changes and infer the gene's contributions to mitochondrial function, reactive oxygen species production, and overall cellular health. This is particularly important for understanding metabolic disorders, where and how energy production is altered.
These cell lines hold significant scientific importance as they serve as powerful tools in both basic and applied research. In clinical settings, they can facilitate drug discovery, elucidate mechanisms of disease, and enable the development of targeted therapies, especially for conditions linked to mitochondrial dysfunction.
Compared to alternative cellular models, SLC25A38 Gene Knockout Cell Lines offer specificity and precision, allowing for a more straightforward understanding of the gene's direct implications on cellular processes. Their utility can lead to more accurate and relevant experimental outcomes and is crucial for studies focusing on mitochondrial biogenesis or metabolic diseases.
For researchers and clinicians alike, the value of these knockout cell lines extends beyond mere experimentation; they represent an opportunity to pioneer advancements in therapeutic strategies and understand fundamental biological mechanisms. With our company’s extensive expertise in genetic engineering and cell line development, we are committed to providing high-quality biological products that enhance research capabilities and contribute to scientific progress.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.