Home / SLC23A1 Knockout Cell Lines

SLC23A1 Knockout Cell Lines

Gene: SLC23A1

Official Full Name: solute carrier family 23 member 1provided by HGNC

Gene Summary: The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two transporters. The encoded protein is active in bulk vitamin C transport involving epithelial surfaces. Previously, this gene had an official symbol of SLC23A2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32450 SLC23A1 Knockout cell line (A549) Human SLC23A1 1:3~1:4 Negative Online Inquiry

Background

SLC23A1 Gene Knockout Cell Lines are meticulously engineered cellular models that lack the SLC23A1 gene, which encodes for a sodium-dependent vitamin C transporter. These cell lines are designed to facilitate comprehensive studies into the biological roles of this transport protein in both physiological and pathological contexts. By systematically disabling the SLC23A1 gene, researchers can better understand its function in vitamin C uptake, antioxidant defenses, and potential implications in disorders such as cancer, metabolic syndrome, and neurodegenerative diseases.

The principal mechanism behind the functionality of the SLC23A1 gene knockout cell lines lies in their ability to mimic deficiencies in vitamin C transport. This unique characteristic allows scientists to elucidate the downstream effects of altered vitamin C levels on cellular metabolism, signaling pathways, and oxidative stress responses. Through comparative analyses with wild-type cell lines, researchers can identify and characterize the gene's influence on various biological processes, providing crucial insights that may lead to novel therapeutic strategies.

Scientifically, these cell lines are invaluable tools in both research and clinical settings. They enable innovative investigations into the role of vitamin C in cellular health, providing a platform for drug development, biomarker discovery, and understanding pathophysiological mechanisms associated with vitamin C deficiency. In clinical applications, findings derived from studies utilizing SLC23A1 knockout models may inform dietary recommendations, enhance therapeutic efficacy in various diseases, and promote personalized medicine approaches.

Compared to alternative models, the SLC23A1 Gene Knockout Cell Lines stand out due to their specificity and precision in targeting a critical nutrient transporter, allowing for more refined experimental outcomes. Unlike conventional cell lines, these knockout models provide a direct means to study the effects of vitamin C transporter deficiency without confounding influences from alternative pathways.

In an era where targeted research is paramount, the SLC23A1 Gene Knockout Cell Lines represent a critical advancement for researchers and clinicians. The ability to study the absence of a specific gene in a controlled environment enhances the potential for meaningful discovery and clinical relevance. Our company prides itself on delivering high-quality biological products backed by rigorous scientific validation, ensuring researchers and clinicians have access to advanced tools that drive innovation and improve outcomes in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.