Gene: SLC22A15
Official Full Name: solute carrier family 22 member 15provided by HGNC
Gene Summary: Organic ion transporters, such as SLC22A15, transport various medically and physiologically important compounds, including pharmaceuticals, toxins, hormones, neurotransmitters, and cellular metabolites. These transporters are also referred to as amphiphilic solute facilitators (ASFs).[supplied by OMIM, Apr 2004]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14081 | SLC22A15 Knockout cell line (HeLa) | Human | SLC22A15 | 1:3~1:6 | Negative | Online Inquiry |
KO14082 | SLC22A15 Knockout cell line (HCT 116) | Human | SLC22A15 | 1:2~1:4 | Negative | Online Inquiry |
KO14083 | SLC22A15 Knockout cell line (HEK293) | Human | SLC22A15 | 1:3~1:6 | Negative | Online Inquiry |
KO14084 | SLC22A15 Knockout cell line (A549) | Human | SLC22A15 | 1:3~1:4 | Negative | Online Inquiry |
SLC22A15 Gene Knockout Cell Lines are specialized cellular models engineered to have a targeted disruption in the SLC22A15 gene, which encodes for a solute carrier protein implicated in the transport of various endogenous metabolites and pharmaceuticals. These cell lines are integral for researchers investigating the physiological roles of SLC22A15 in drug metabolism, cellular detoxification, and physiological processes such as nutrient transport and signaling pathways.
The key functionality of SLC22A15 Gene Knockout Cell Lines arises from their ability to elucidate the biological consequences of the loss of SLC22A15 function. By systematically removing this gene, researchers can study phenotypic changes, drug response alterations, and metabolic shifts in a controlled environment. Mechanistically, these knockout cell lines allow for the investigation of protein interactions, alterations in cellular pathways, and the evaluation of therapeutic targets, contributing to our understanding of pathology at a cellular level.
The scientific importance of these cell lines is evident in both basic and applied research settings. They serve as valuable tools for pharmacokinetic studies, toxicology assessments, and exploring potential gene therapies. Researchers in academia and pharmaceutical industries can utilize these models to better understand drug interactions and to screen for novel compounds with enhanced efficacy and reduced side effects.
SLC22A15 Gene Knockout Cell Lines offer significant advantages over traditional model systems. Unlike wild-type cells that can exhibit variable gene expression and complexity, these knockout lines provide a consistent and reproducible background for experimental analyses. Additionally, their targeted gene disruption enables straightforward interpretation of experimental outcomes, making it easier to identify specific gene functions and drug effects.
These cell lines represent an essential asset for researchers and clinicians focusing on precision medicine, drug development, and molecular biology. By aiding in the discovery and development of next-generation therapeutics, they can accelerate advancements in personalized medicine approaches.
At our company, we pride ourselves on our cutting-edge biological product offerings, backed by extensive expertise in genomics and cellular biology. We are committed to providing high-quality research tools that empower scientists to push the boundaries of discovery and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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