Gene: SLC16A13
Official Full Name: solute carrier family 16 member 13provided by HGNC
Gene Summary: Predicted to enable monocarboxylic acid transmembrane transporter activity. Predicted to be involved in carboxylic acid transmembrane transport. Located in Golgi apparatus and cytosol. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37535 | SLC16A13 Knockout cell line (HeLa) | Human | SLC16A13 | 1:3~1:6 | Negative | Online Inquiry |
KO37536 | SLC16A13 Knockout cell line (HCT 116) | Human | SLC16A13 | 1:2~1:4 | Negative | Online Inquiry |
KO37537 | SLC16A13 Knockout cell line (HEK293) | Human | SLC16A13 | 1:3~1:6 | Negative | Online Inquiry |
KO37538 | SLC16A13 Knockout cell line (A549) | Human | SLC16A13 | 1:3~1:4 | Negative | Online Inquiry |
SLC16A13 Gene Knockout Cell Lines are specially engineered cellular models that have had the SLC16A13 gene deactivated to study its function and impact in various biological processes. This gene encodes a member of the solute carrier family, known for facilitating the transport of monocarboxylates, which are critical in metabolic pathways, particularly in the context of cellular energy homeostasis and lactate transport. By knocking out this gene, researchers can investigate the subsequent changes in cellular metabolism, signaling pathways, and overall cellular physiology.
The mechanism through which SLC16A13 gene knockout exerts its effects involves an alteration in the transport dynamics of key metabolites, providing valuable insights into how shifts in metabolic environments can lead to pathophysiological changes. This is particularly important in understanding diseases such as cancer, where the metabolic rewiring of cells is a hallmark feature. In clinical and research settings, these cell lines serve as invaluable tools for drug discovery, disease modeling, and therapeutic development, particularly for conditions linked to metabolic dysfunction.
One of the standout advantages of using SLC16A13 Gene Knockout Cell Lines is their specificity and reliability as model systems. Unlike traditional cell lines, these knockout models provide clear insights into the gene's function, paving the way for more targeted investigations into therapeutic strategies. Researchers can draw direct correlations between gene absence and cellular behavior, thus garnering more accurate results than those obtained from wild-type cell lines.
For researchers and clinicians focused on metabolic pathways, these knockout cell lines represent a significant leap forward in the fidelity of experimental data, enhancing the scientific understanding of critical biological processes. They enable the efficient screening of potential therapeutic agents while providing a platform for elucidating various metabolic disorders.
Our company takes pride in its expertise in genetic engineering and cell line development, ensuring that our SLC16A13 Gene Knockout Cell Lines maintain the highest standards of quality and reproducibility. With a committed focus on advancing biological research, we provide essential tools that aid scientists in their quest to unravel the complexities of human health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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